Category Archives: Biomedical interventions

Key take-home messages The use of prophylactics in the prevention of HIV transmission has traditionally centered on the male condom. Negotiation of condom use has therefore been largely male-centric. The...

Key take-home messages HIV/HCV co-infection increases risk of vertical transmission of both HCV and HIV, and cesarean delivery is recommended. In the studies identified, few gender differences were found to...

Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...

Key take-home messages Pregnant women with HIV have distinct psychosocial needs that must be addressed. Very little research has investigated the most effective means of delivering psychosocial support to pregnant...

Key take-home messages Men who have sex with men who have used a female condom often complain of irritation, bunching up, unpleasant texture, noise, discomfort upon insertion, lack of pleasure,...

Key take-home messages There were fewer studies published on the potential use of non-occupational PEP (nPEP) among men who have sex with men than those on PrEP. Although 47% to...

Key take-home messages Findings from recent studies have highlighted the potential for antiretroviral therapy to prevent HIV by reducing an HIV-positive person’s viral load. Prevention experts are concerned that active...

Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...

Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...

BACKGROUND: Worldwide, nearly 18 million women of reproductive age are living with HIV-1. Although increased access to antiretroviral therapy (ART) during pregnancy has significantly reduced HIV-1 mother-to-child transmission (MTCT), a...

Virtual elimination of mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) is a global target. A review of the literature was conducted using medical databases and health department websites to...

BACKGROUND AND PURPOSE: The World Health Organizations (WHO) strategy is to eliminate pediatric HIV. HIV prevention guidelines in high-income countries recommend mothers living with HIV avoid breastfeeding. Yet, breastfeeding is...