Category Archives: Biomedical interventions
Integration of neonatal and child health interventions with pediatric HIV interventions in global health
Background/Objectives: In the last decade, many strategies have called for integration of HIV and child survival platforms to reduce missed opportunities and improve child health outcomes. Countries with generalized HIV...
Socio-structural factors influencing the prevention of mother-to-child transmission of HIV in the democratic republic of the Congo: A systematic review
Introduction The Democratic Republic of the Congo (DRC) had the second-highest mother-to-child HIV transmission rate in Sub-Saharan Africa at 29% in 2013, however the uptake of preventive services for mother-to-child...
Male partner involvement in the utilization of hospital delivery services by pregnant women living with HIV in sub Saharan Africa: A systematic review and meta-analysis
Objective The level of male partner involvement in hospital delivery by pregnant women living with HIV in sub Saharan Africa (SSA) is low. We conducted a systematic review and meta-analysis...
Elimination of HIV transmission through novel and established prevention strategies among people who inject drugs
Despite the effectiveness of existing HIV prevention strategies for people who inject drugs (PWID), uncontrolled outbreaks of HIV among this group are common and occur around the world. In this...
Incidence of sexually transmitted infections in men who have sex with men and who are at substantial risk of HIV infection – A meta-analysis of data from trials and observational studies of HIV pre-exposure prophylaxis
BACKGROUND: Men who have sex with men (MSM) and who engage in condomless anal intercourse with casual partners are at high risk of acquiring sexually transmitted infections (STIs), but reliable...
The impact of approaches in improving male partner involvement in the prevention of mother-to-child transmission of HIV on the uptake of safe infant feeding practices by HIV positive women in sub-Saharan Africa. A systematic review and meta-analysis
BACKGROUND: The low level of male partner involvement in Prevention of Mother to Child Transmission of HIV services such as safe infant feeding practices poses a serious challenge to the...
Chemsex behaviours among men who have sex with men: A systematic review of the literature
BACKGROUND: ‘Chemsex’ is the use of drugs before or during planned sexual events to facilitate, enhance, prolong and sustain the experience. Drugs associated with chemsex are methamphetamine, GHB/GBL, mephedrone, cocaine...
Effectiveness of oral pre-exposure prophylaxis (PrEP) for HIV
Key take-home messages Oral PrEP (tenofovir disoproxil fumarate with emtricitabine) is highly protective against HIV acquisition across various populations and across different dosing schedules. Open label and demonstration projects in...
A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis
Background: Pre-exposure prophylaxis, or PrEP, has been shown to be effective at reducing the risk of HIV infection, yet persons at-risk for acquiring HIV exhibit suboptimal uptake of and adherence...
Quality of HIV websites with information about pre-exposure prophylaxis or treatment as prevention for men who have sex with men: A systematic evaluation
BACKGROUND: Knowledge and uptake of high-efficacy HIV prevention strategies such as pre-exposure prophylaxis (PrEP) and treatment as prevention (TasP) remain low among men who have sex with men (MSM) who...
A review of approaches used to increase awareness of pre-exposure prophylaxis (PrEP) in the United States
PrEP is an important and useful HIV prevention strategy, yet awareness remains low among at-risk populations in the United States and elsewhere in the world. As previous studies have shown...
