Category Archives: Biomedical interventions

Topical treatment of anogenital human papillomavirus infection in male patients

2009

Background: Human papillomavirus (HPV) -associated anogenital warts have a prevalence of up to 78% in sexually active men. Some HPV subtypes bear a considerable oncogenic potential. Materials & methods: Original...

Cost-effectiveness of antenatal HIV-testing: Reviewing its pharmaceutical and methodological aspects

2004

This paper reviews the pharmacoeconomic aspects of antenatal testing for HIV. HIV is a retrovirus which is transmitted among humans through sexual contact, infected blood or blood products (needle sharing...

Nonoccupational postexposure prophylaxis for human immunodeficiency virus in Sub-Saharan Africa: A systematic review

2011

Both HIV and sexual assault remain major public health problems in Sub-Saharan Africa. This review examines the state of the science regarding provision of non-occupational post-exposure prophylaxis following sexual assault...

Effectiveness of HIV prevention interventions in developing countries

2000

Objective: To review the effectiveness of projects and programs in developing countries that aim to reduce sexual transmission of HIV infection or transmission related to injection drug use. Design: We...

Helping our patients take HIV pre-exposure prophylaxis (PrEP): A systematic review of adherence interventions

2014

OBJECTIVES: Adherence is critical for maximizing the effectiveness of pre-exposure prophylaxis (PrEP) in preventing HIV infection. Strategies for promoting adherence to HIV treatment, and their potential application to PrEP adherence,...

Male involvement in prevention programs of mother to child transmission of HIV: A systematic review to identify barriers and facilitators

2013

BACKGROUND: Many reports point to the beneficial effect of male partner involvement in programs for the prevention of mother-to-child-transmission (PMTCT) of HIV in curbing pediatric HIV infections. This paper summarizes...

Impact of antiretroviral drugs in pregnant women and their children in Africa: HIV resistance and treatment outcomes

2013

The global community has committed itself to eliminating new pediatric HIV infections by 2015 and improving maternal, newborn, and child health and survival in the context of HIV. Such objectives...

Topical microbicides for prevention of sexually transmitted infections

2012

BACKGROUND: Two decades of research on topical microbicides for prevention of sexually transmitted infections (STIs) have had limited success. However, new microbicide randomised controlled trial (RCT) data have recently been...

Effectiveness of sport-based HIV prevention interventions: A systematic review of the evidence.

2013

Interest in sport as a tool for behavioral HIV prevention has grown substantially in the past decade. With dozens of organisations now using sport-based HIV prevention (SBHP) approaches and upcoming...

Influence of maternal human immunodeficiency virus (HIV) co-infection on vertical transmission of hepatitis C virus (HCV): A meta-analysis

2003

BACKGROUND: Maternal co-infection with human immunodeficiency virus (HIV) has been implicated as a potentially important co-factor for enhanced vertical transmission of hepatitis C virus (HCV). In previous reports, however, methodological...

Nonoccupational postexposure prophylaxis following sexual assault in industrialized low-HIV-prevalence countries: A review

2012

Although available for over a decade, use of nonoccupational postexposure prophylaxis (nPEP) remains controversial in the United States. There are concerns over sexual assault survivors’ adherence, or lack thereof, leading...

Integrating prevention of mother-to-child HIV transmission programs to improve uptake: A systematic review

2012

Background: We performed a systematic review to assess the effect of integrated perinatal prevention of mother-to-child transmission of HIV interventions compared to non- or partially integrated services on the uptake...

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