Category Archives: Biomedical interventions

Stigma in the HIV/AIDS epidemic: A review of the literature and recommendations for the way forward

2008

Although stigma is considered a major barrier to effective responses to the HIV/AIDS epidemic, stigma reduction efforts are relegated to the bottom of AIDS programme priorities. The complexity of HIV/AIDS-related...

Randomised controlled trials in Africa of HIV and AIDS: Descriptive study and spatial distribution

2005

OBJECTIVES: To identify and describe randomised controlled trials on HIV and AIDS conducted in Africa and to map their spatial distribution using exact geographic coordinates. DESIGN: Construction and analysis of...

Antiretroviral interventions for preventing breast milk transmission of HIV

2014

BACKGROUND: An estimated 260,000 children under the age of 15 years acquired HIV infection in 2012. As much as 42% of mother-to-child transmission is related to breastfeeding. Antiretroviral prophylaxis for...

Male circumcision and risk of HIV infection in sub-Saharan Africa: A systematic review and meta-analysis

2000

OBJECTIVE: To systematically review studies of male circumcision and the risk of HIV-1 infection in men in sub-Saharan Africa, and to summarize the findings in a meta-analysis. DESIGN: A meta-analysis...

Interventions for reducing the risk of mother-to-child transmission of HIV infection

2002

BACKGROUND: At the end of 1998 over 33 million people were infected with the human immunodeficiency virus (HIV) and over one million children had been infected from their mothers. OBJECTIVES:...

Adherence challenges with drugs for pre-exposure prophylaxis to prevent HIV infection

2014

Background There are 34 million people living with human immunodeficiency virus (HIV) worldwide and each year this number increases. Until a vaccine is discovered, the prevention of new HIV infections...

Adherence to HIV post-exposure prophylaxis in victims of sexual assault: A systematic review and meta-analysis

2012

OBJECTIVE: To assess adherence to post-exposure prophylaxis (PEP) for the prevention of HIV infection in victims of sexual assault. METHODS: The authors carried out a systematic review, random effects meta-analysis...

Young people’s knowledge, attitude, and behaviour on STI/HIV/AIDS in the context of Nepal: A systematic review

2009

Background: Sexual and reproductive health of young people has become a major health problem in recent decades. Recent and rapidly increasing Human Immune Defi ciency Virus (HIV) rates show an...

Efficacy of antiretroviral drugs in reducing mother-to-child transmission of HIV in Africa: A meta-analysis of published clinical trials

2008

Antiretroviral drugs (ARVs) have been shown to be efficacious in decreasing mother-to-child transmission (MTCT) of HIV. A summary estimate of the efficacy of ARVs in reducing MTCT is important for...

Systematic review of the efficacy of antiretroviral therapies for reducing the risk of mother-to-child transmission of HIV infection

2007

OBJECTIVE: To evaluate the efficacy of antiretroviral therapies in reducing the risk of mother-to-child transmission of HIV infection. METHODS: Systematic review and meta-analysis of randomized controlled trials. Clinical trials of...

HIV and male circumcision – A systematic review with assessment of the quality of studies

2005

This Cochrane systematic review assesses the evidence for an interventional effect of male circumcision in preventing acquisition of HIV-1 and HIV-2 by men through heterosexual intercourse. The review includes a...

Antiretroviral therapy in prevention of HIV and TB: Update on current research efforts

2011

There is considerable scientific evidence supporting the use of antiretroviral therapy (ART) in prevention of human immunodeficiency virus (HIV) and tuberculosis (TB) infections. The complex nature of the HIV and...

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