Category Archives: Drug use behaviours/harm reduction
HIV prevention for South African youth: which interventions work? A systematic review of current evidence
BACKGROUND: In South Africa, HIV prevalence among youth aged 15-24 is among the world’s highest. Given the urgent need to identify effective HIV prevention approaches, this review assesses the evidence...
Non-occupational postexposure prophylaxis for HIV: A systematic review
OBJECTIVES: To review the evidence on the clinical effectiveness and cost-effectiveness of non-occupational postexposure prophylaxis (PEP) for HIV. DATA SOURCES: Eleven electronic databases were searched from inception to December 2007....
Meta-analyses of seven of the National Institute on Drug Abuse’s principles of drug addiction treatment
Of the 13 principles of drug addiction treatment disseminated by the National Institute on Drug Abuse (NIDA), 7 were meta-analyzed as part of the Evidence-based Principles of Treatment (EPT) project....
Utilizing buprenorphine-naloxone to treat illicit and prescription-opioid dependence
OBJECTIVES: To review current evidence on buprenorphine-naloxone (bup/nx) for the treatment of opioid-use disorders, with a focus on strategies for clinical management and office-based patient care. QUALITY OF EVIDENCE: Medline...
Brief report: Methadone treatment of injecting opioid users for prevention of HIV infection
OBJECTIVE: To assess the effects of oral substitution treatment for opioid-dependent injecting drug users on HIV risk behaviors and infections. DATA SOURCES: Multiple electronic databases were searched. Reference lists of...
Meta-analysis of interventions for reducing number of sexual partners and drug and alcohol abuse among people living with HIV/AIDS
OBJECTIVE: To perform a systematic review and meta-analysis of the efficacy of risk reduction interventions on HIV-related risk behaviors among people living with HIV/AIDS (PLWHA). METHODS: Studies included in the...
Efficacy of HIV Prevention Interventions in Latin American and Caribbean Nations, 1995-2008: A Meta-Analysis
This meta-analysis synthesized 37 HIV prevention interventions (from 28 studies) that were evaluated in Latin American and Caribbean nations. These studies were obtained through systematic searches of English, Spanish, and...
HIV and HCV prevalence among entrants to methadone maintenance treatment clinics in China: A systematic review and meta-analysis
Background: Methadone maintenance treatment (MMT) was implemented in China since 2004. It was initiated in 8 pilot clinics and subsequently expanded to 738 clinics by the end of 2011. Numerous...
