Category Archives: Drug use behaviours/harm reduction
Effectiveness of take-home naloxone programs and availability of naloxone nasal spray in different jurisdictions
Key take-home messages There is wide support of take-home naloxone programs as they are associated with decreased mortality, but there is some evidence that take-home naloxone alone may not be...
Electronic and other new media technology interventions for HIV care and prevention: A systematic review
INTRODUCTION: Electronic and other new media technologies (eHealth) can facilitate large-scale dissemination of information and effective delivery of interventions for HIV care and prevention. There is a need to both...
Permanent supportive housing with housing first to reduce homelessness and promote health among homeless populations with disability: A community guide systematic review
CONTEXT: Poor physical and mental health and substance use disorder can be causes and consequences of homelessness. Approximately 2.1 million persons per year in the United States experience homelessness. People...
Human immunodeficiency virus prevention for people who use drugs: Overview of reviews and the ICOS of PICOS
BACKGROUND: This article summarizes the results from systematic reviews of human immunodeficiency virus (HIV) prevention interventions for people who use drugs (PWUD). We performed an overview of reviews, meta-analysis, meta-epidemiology,...
The prevalence and factors associated with alcohol use disorder among people living with HIV/AIDS in Africa: A systematic review and meta-analysis
BACKGROUND: Alcohol use disorder (AUD) in HIV/AIDS patient’s decreases adherence and effectiveness of medications and help-seeking to HIV/AIDS care and treatment. This study, therefore, assessed the average 1ƒ_%year prevalence and...
Interventions to improve HIV care continuum outcomes among individuals released from prison or jail: Systematic literature review
BACKGROUND: HIV care continuum outcomes deteriorate among people returning from incarceration. Interventions to improve care outcomes post-incarceration have been characterized by substantial heterogeneity in approach, outcome metrics, and results. A...
Community-based psychosocial substance use disorder interventions in low-and-middle-income countries: A narrative literature review
BACKGROUND: Mental health and substance use disorders (SUDs) are the world’s leading cause of years lived with disability; in low-and-middle income countries (LIMCs), the treatment gap for SUDs is at...
Acute and early HIV infection screening among men who have sex with men, a systematic review and meta-analysis
INTRODUCTION: Screening for acute and early HIV infections (AEHI) among men who have sex with men (MSM) remains uncommon in sub-Saharan Africa (SSA). Yet, undiagnosed AEHI among MSM and subsequent...
Methadone maintenance therapy service components linked to improvements in HIV care cascade outcomes: A systematic review of trials and observational studies
BACKGROUND: The beneficial links between engagement in methadone maintenance therapy (MMT) and HIV treatment outcomes have been extensively described. Nevertheless, people who use drugs (PWUD) continue to experience suboptimal HIV...
Attributes of HIV infection over decades (1982–2018): A systematic review and meta-analysis
Understanding the risk factors for HIV infection is the foundation of successful preventive strategies, which must bundle sociocultural, behavioural and biomedical interventions to halt disease transmission. We aimed in this...
Injecting risk behaviours amongst people who inject drugs: A global multi-stage systematic review and meta-analysis
BACKGROUND: Injecting risk behaviour, such as receptive sharing of injecting equipment and/or re-using one’s equipment, is associated with bloodborne virus transmission and infections in people who inject drugs (PWID). We...
