Category Archives: Substance Use
Mental health service delivery in South Africa from 2000 to 2010: One step forward, one step back
Objectives. To identify progress and challenges in mental healthcare in South Africa, as well as future mental health services research priorities. Method. A systematic review of mental health services research....
Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection
Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...
Antiretroviral adherence interventions: Translating research findings to the real world clinic
The success of potent combination antiretroviral therapy (ART) for HIV infection is compromised primarily by failure to maintain optimal levels of adherence over the long term. Recent reviews suggest behavioral...
Ethical and regulatory considerations in HIV prevention studies employing respondent-driven sampling
OBJECTIVE: To review the scientific, ethical, and regulatory literature because no official guidance exists on remuneration for participant-driven recruitment or on investigators’ responsibilities for informing participants of their discordant partnerships....
Socio-demographic characteristics and behavioral risk factors of female sex workers in sub-saharan Africa: A systematic review
Sex work remains an important contributor to HIV transmission within early, advanced and regressing epidemics in sub-Saharan Africa, but its social and behavioral underpinnings remain poorly understood, limiting the impact...
The association between HIV infection and alcohol use: A systematic review and meta-analysis of African studies
To summarize the association between alcohol use and human immunodeficiency virus (HIV) infection based on studies conducted in Africa, EMBASE and PubMed were searched for African studies that related alcohol...
A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals
OBJECTIVE: To estimate summary standardized incidence ratios (SIRs) of non-AIDS cancers among HIV-infected individuals compared with general population rates overall and stratified by gender, AIDS, and highly active antiretroviral therapy...
Are females who inject drugs at higher risk for HIV infection than males who inject drugs: An international systematic review of high seroprevalence areas
Objective: There are multiple reasons why females who inject drugs may be more likely to become infected with HIV than males who inject drugs. Where this is the case, special...
HIV infection associated post-traumatic stress disorder and post-traumatic growth – A systematic review
The phenomenon of post-traumatic stress has been well documented in the literature as a lasting mental health condition associated with exposure to traumatic life events. The diagnosis and experience of...
Effectiveness of different models of case management for substance-abusing populations
Case management has been implemented in substance abuse treatment to improve (cost-) effectiveness, but controversy exists about its potential to realize this objective. A systematic and comprehensive review of peer-reviewed...
