Category Archives: Nonmedicinal drugs
A systematic review of evidence-based workplace prevention programmes that address substance abuse and HIV risk behaviours
The purpose of the systematic review was to determine the effectiveness of workplace substance abuse prevention programmes that also address substance-related HIV risks. A search of major electronic databases was...
Targeting the SAVA (Substance Abuse, Violence, and AIDS) syndemic among women and girls: A global review of epidemiology and integrated interventions
OBJECTIVES: Multiple pathways link gender-based violence (GBV) to HIV and other sexually transmitted infections among women and girls who use or inject drugs. The aim of this article is to...
Drug-drug interactions with antiviral agents in people who inject drugs (PWID) requiring substitution therapy
OBJECTIVE: To describe potential drug-drug interactions in the area of HIV/hepatitis C virus (HCV) coinfection and injection drug use, including those between antiretrovirals (ARVs), direct-acting antivirals (DAAs), and opioid-agonist therapy,...
Comparisons of disparities and risks of HIV infection in black and other men who have sex with men in Canada, UK, and USA: A meta-analysis
BACKGROUND: We did a meta-analysis to assess factors associated with disparities in HIV infection in black men who have sex with men (MSM) in Canada, the UK, and the USA....
Mortality among people who inject drugs: A systematic review and meta-analysis
OBJECTIVE: To systematically review cohort studies of mortality among people who inject drugs, examine mortality rates and causes of death in this group, and identify participant- and study-level variables associated...
Utilizing buprenorphine-naloxone to treat illicit and prescription-opioid dependence
OBJECTIVES: To review current evidence on buprenorphine-naloxone (bup/nx) for the treatment of opioid-use disorders, with a focus on strategies for clinical management and office-based patient care. QUALITY OF EVIDENCE: Medline...
Global epidemiology of injecting drug use and HIV among people who inject drugs: A systematic review
Background: Injecting drug use is an increasingly important cause of HIV transmission in most countries worldwide. Our aim was to determine the prevalence of injecting drug use among individuals aged...
Effectiveness of protease inhibitor monotherapy versus combination antiretroviral maintenance therapy: A meta-analysis
BACKGROUND: The unparalleled success of combination antiretroviral therapy (cART) is based on the combination of three drugs from two classes. There is insufficient evidence whether simplification to ritonavir boosted protease...
Redressing the epidemics of opioid overdose and HIV among people who inject drugs in Central Asia: The need for a syndemic approach
BACKGROUND: Accumulating evidence suggests that opioid overdose and HIV infection are burgeoning intertwined epidemics among people who inject drugs (PWID) in Central Asia. To date, however, research on overdose and...
Meta-analysis of interventions for reducing number of sexual partners and drug and alcohol abuse among people living with HIV/AIDS
OBJECTIVE: To perform a systematic review and meta-analysis of the efficacy of risk reduction interventions on HIV-related risk behaviors among people living with HIV/AIDS (PLWHA). METHODS: Studies included in the...
