Category Archives: Health Systems

Long-acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re-suppression outcomes in virally suppressed individuals living with HIV

2025

Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking....

Evaluating the impact of COVID-19 on the HIV care continuum across global income levels: A mixed-methods systematic review

2025

BACKGROUND: The COVID-19 pandemic caused significant disruptions to global healthcare systems, including essential services along the HIV care continuum (HCC). While several studies have examined these impacts in specific countries...

Psychosocial experience and coping of AIDS patients about the disease: A systematic review and qualitative meta-synthesis

2025

AIM: To systematically integrate the psychosocial experiences and coping mechanisms of AIDS patients after the disease, and to understand their true feelings, in order to provide a basis for better...

Reducing HIV risk behaviors among Black women living with and without HIV/AIDS in the U.S.: A systematic review

2025

This systematic review provides an examination of the status of HIV/AIDS prevention interventions for Black, heterosexual women in the U.S. from 2012 to 2019. Using PRISMA guidelines, 28 interventions were...

Incidence and predictors of attrition among children on antiretroviral therapy in Ethiopia: A systematic review and meta-analysis

2025

Objective To estimate the pooled attrition rate among HIV-infected children receiving antiretroviral therapy (ART) and identify predictors of attrition in Ethiopia. Design Systematic review and meta-analysis. Data sources PubMed, HINARI,...

Menstrual health and menstrual equity for women living with HIV: A minireview

2025

Despite the advent of ART and the conversion of human immunodeficiency virus (HIV) into a chronic disease, little is known regarding the experiences of women living with HIV (WLWH) in...

Evidence-based interventions targeting mental health problems in adolescents living with HIV: A scoping review

2025

Adolescents living with HIV are at an increased risk of experiencing mental health challenges, impacting their overall well-being and treatment adherence. Evidence-based interventions are crucial to addressing these issues; however,...

Assessing the landscape for PrEP provisions in prisons: A systematic review

2025

This systematic review aims to review awareness and willingness for PrEP use in the prison complex and the factors influencing PrEP uptake among people incarcerated in state or federal prisons....

Syndemic interactions between HIV/AIDS, mental health conditions, and non-communicable diseases in sub-Saharan Africa: A scoping review of contributing factors

2025

INTRODUCTION: The syndemic framework provides a critical lens for understanding the complex interplay between HIV/AIDS, mental health (MH) conditions, and non-communicable diseases (NCDs) in Africa. This scoping review explores how...

Acceptability, needs, concerns, and barriers to digital-based interventions for the prevention of mother-to-child transmission of HIV: Systematic review and qualitative meta-aggregation

2025

BACKGROUND: Digital-based interventions have the potential to support initiatives for the prevention of mother-to-child HIV transmission (PMTCT). Nevertheless, reviews to explore experiences and perspectives toward digital-based interventions in mothers living...

Studied factors and metrics of patient portal use among people with HIV: A rapid scoping review

2025

For people living with HIV (PLHIV), patient portals could facilitate access to personal health records while promoting self-management and retention in care. Given the apparent heterogeneity in the studied factors...

Oral pre-exposure prophylaxis initiation, continuation and adherence among pregnant and postpartum women receiving antenatal and postnatal care: A systematic review

2025

INTRODUCTION: In 2023, one-fourth of new HIV acquisitions in children globally resulted from vertical transmission following incident HIV during pregnancy or breastfeeding. Oral pre-exposure prophylaxis (PrEP) with tenofovir disoproxil and...

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