Category Archives: Health Systems

Sexually transmitted infection prevalence and testing coverage among people who inject drugs: A systematic review

2025

Background: Individual- and structural-level factors place people who inject drugs at excess risk of sexually transmitted infections (STI). We reviewed existing evidence on STI prevalence and testing coverage among this...

Use of self-test to increase HIV testing among men who have sex with men and transgender women—Overview of systematic reviews

2025

ABSTRACT Human Immunodeficiency Virus (HIV) infection is stigmatizing, especially for key populations, who are disproportionately affected by Sexually Transmitted Infections (STIs). The stigma and discrimination suffered by these groups are...

How do migrants living with HIV adhere to the HIV care process in high-income countries? A systematic review

2025

BACKGROUND: In high-income countries (HICs), migrants living with HIV (MLHIV) are more likely than other HIV subpopulations to encounter problems which hamper their adherence to the care process; these include...

Characterization and stratification of risk factors of stroke in people living with HIV: A theory-informed systematic review

2025

Background Identification and stratification of risk factors for stroke among individuals living with HIV (PLWH) will facilitate primary prevention and prognostication, as well as strategies aimed at optimizing neurorehabilitation. This...

HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: A systematic review of effectiveness, case studies, values and preferences, and costs

2025

INTRODUCTION: Post-exposure prophylaxis (PEP) for HIV prevention has been inadequately promoted, provided and used. Expanded access and task sharing could increase the HIV prevention impact of PEP, but scientific evidence...

User preferences on long-acting pre-exposure prophylaxis for HIV prevention in Eastern and Southern Africa: A scoping review

2025

BACKGROUND: Novel formulations for pre-exposure prophylaxis (PrEP) such as injectables, implants, and intravaginal rings are emerging as long-acting alternatives to daily pills for the prevention of HIV. Eastern and Southern...

Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: A systematic review

2025

Background To stem rising fatal overdoses and other substance use/use disorder (SUD)-related harms, communities are turning to low-barrier harm reduction strategies, such as harm reduction-focused vending machines (VMs) that distribute...

Preferences for long-acting HIV pre-exposure prophylaxis among women of reproductive age in low- and middle-income countries: A systematic review

2025

HIV remains a major public health problem in low- and middle-income countries (LMICs). While oral pre-exposure prophylaxis (PrEP) is documented as safe and effective for HIV prevention, adherence remains a...

What services, interventions and support are available for people with HIV in England to manage their overall health and wellbeing? A scoping review

2025

OBJECTIVES: The average age of a person living with HIV in high-income countries is increasing, as are rates of multimorbidity and frailty. To meet these needs, existing services must adapt....

Ambivalent experiences of people in treatment for tuberculosis-HIV coinfection: A meta-synthesis of qualitative studies

2025

This study examined the scientific literature, by means of a systematic review with meta-synthesis (PROSPERO No. CRD42023410141), to discover the experiences of people undergoing treatment for tuberculosis-HIV coinfection. Ten databases...

Assessing the impact of digital communication tools on oral PrEP adherence: A systematic review and meta-analysis

2025

This systematic review and meta-analysis evaluated the effect of digital communication tools (e.g., text message reminders) on improving daily oral HIV pre-exposure prophylaxis (PrEP) adherence. Searching PubMed, Embase, Web of...

Safer opioid supply clients’ values and preferences: A systematic review and thematic synthesis of qualitative research

2025

QUESTION: What are the values and preferences of safer opioid supply clients? STUDY SELECTION AND ANALYSIS: We conducted a systematic review of qualitative studies on safer opioid supply client experiences...

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