Category Archives: Health Systems
Seroprevalence of transfusion-transmitted infections among blood donors in India: A systematic review and meta-analysis
BACKGROUND AND OBJECTIVES: Blood transfusion is essential in healthcare but carries inherent risks of human immunodeficiency virusAÿ(HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and malaria transmission. National...
Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: A systematic review and meta-analysis
Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...
Prevalence and factors influencing HIV testing behavior in adolescents and young adults: A systematic review and meta-analysis
Objective To systematically evaluate the prevalence and influencing factors of human immunodeficiency virus (HIV) testing among adolescents and young adults (10–25 years old), providing a reference for optimizing testing strategies and...
Artificial intelligence for HIV care: A global systematic review of current studies and emerging trends
INTRODUCTION: Artificial intelligence (AI) and, in particular, machine learning (ML) have emerged as transformative tools in HIV care, driving advancements in diagnostics, treatment monitoring and patient management. The present review...
Breastfeeding knowledge, attitudes and practices of HIV-positive women in Africa: A systematic review
BACKGROUND: Breastfeeding is essential for ensuring the health and survival of children, particularly in regions where diarrhoea, pneumonia and malnutrition are common causes of child mortality. In sub-Saharan Africa, over...
Hepatitis C increases acute myocardial infarction risk in people living with HIV: A systematic review and meta-analysis
BackgroundHepatitis C virus (HCV) coinfection is common among people living with HIV (PLWH) and is associated with adverse outcomes. However, the specific association between HCV coinfection and the risk of...
HIV-related mortality time trends among children and young adolescents on antiretroviral therapy by age, treatment duration, and region: A systematic review and meta-regression analysis
Background: Past cohort studies have examined mortality among children and young adolescents (aged 0–14 years) who have received antiretroviral therapy (ART), but no systematic reviews have been undertaken to synthesise these...
The impact of antiretroviral therapy (ART) on HPV persistence and cervical cancer progression among women with HPV/HIV co-infection: A systematic review
Cervical cancer remains the leading cause of cancer-related morbidity and mortality among women globally, particularly in low- and middle-income countries. Women living with HIV are at risk of persistent high-risk...
State of HIV research in Venezuela: A systematic review
BACKGROUND: Venezuela’s recent economic and political instability has severely compromised its healthcare infrastructure, impacting the management of infectious diseases, including human immunodeficiency virus (HIV). This disruption hinders progress towards the...
HIV status and the risk of typhoid fever and iNTS: A systematic review and meta-analysis
OBJECTIVES: The WHO recommends prioritising people living with HIV (PLHIV) for typhoid vaccination, but evidence for increased typhoid fever risk is inconsistent. We aimed to evaluate whether HIV infection alters...
Rapid start with bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) as initial treatment in people with human immunodeficiency virus-1 (HIV-1): A systematic literature review of clinical and patient-reported outcomes
BACKGROUND: Treatment guidelines recommend rapid antiretroviral therapy (ART) initiation among eligible people with HIV to improve treatment outcomes and reduce HIV transmission. Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF), an integrase strand transfer inhibitor-based...
