Category Archives: Health Systems

Cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (2019-2025): A systematic review

2025

INTRODUCTION: This systematic review synthesizes recent evidence on the cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (SSA), where over 70% of the global HIV burden resides. METHODS: Following PRISMA...

Single-session interventions to enhance HIV outcomes among adolescents and young adults: A systematic scoping review and implications for integrating HIV and mental health services

2025

Significant progress has been made in HIV prevention and treatment for adolescents and young adults (AYA), but integrating mental healthcare remains essential to address risks and improve treatment engagement. Single-session...

HIV and tuberculosis co-infection in non-European migrants in Europe: A systematic review and meta-analysis

2025

Background Even though HIV-TB co-infection is an emerging public health issue among migrants in European countries, the number of related articles has shown a decreasing trend. Methods To better estimate...

Probability of vertical HIV transmission: A systematic review and meta-regression

2025

Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...

Network meta-analytical investigations of the performance of HIV combination prevention strategies for Indigenous populations

2025

BACKGROUND: Indigenous populations worldwide face a disproportionate burden of HIV due to structural inequities, cultural marginalization, and limited access to health services. Despite growing recognition of the need for culturally...

The latest trends and evolutoin of HIV medication management: A systematic review

2025

The last 10 years have witnessed various significant progresses in the management and treatment of HIV/AIDS, including the development of novel HIV prevention technologies and safer and potent antiretroviral medications....

Cost-effectiveness of HIV prevention strategies: A systematic review of economic evaluations

2025

BACKGROUND: HIV/AIDS continues to pose a significant global health challenge, especially in low- and middle-income countries. Economic evaluations are essential to identify cost-effective prevention strategies and allocate limited healthcare resources...

Effectiveness of HIV health education interventions on the MSM population: A meta-analysis

2025

Men who have sex with men (MSM) face a heightened risk of HIV, presenting a significantpublic health issue. This meta-analysis evaluates the effectiveness of HIV health educationfor MSM by examining...

Mobile health intervention tools promoting HIV pre-exposure prophylaxis among adolescent girls and young women in sub-Saharan Africa: Scoping review

2025

BACKGROUND: In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited...

Implementation of trauma-informed care into clinical HIV prevention and care settings: A decade of limited progress

2025

PURPOSE OF THE REVIEW: Trauma is common among people living with or at risk for HIV and associated with increased HIV risk and worse HIV care outcomes. Trauma-informed care (TIC)...

Cost-effectiveness analyses of adolescent- and young-adult-focused HIV interventions incorporating HIV transmission: A scoping review of modeling methods and proposed guidance

2025

BACKGROUND: Adolescents and young adults (AYA) are disproportionately affected by human immunodeficiency virus (HIV) globally, with high-burden population subgroups differing across regions. Cost-effectiveness modeling analyses of AYA-focused HIV interventions have...

Guidelines for the transfer of people living with HIV attending primary healthcare facilities in South Africa: A scoping review

2024

People living with HIV may move between health facilities: this is called ‘transfer’, and includes up- and down-referral based on clinical condition and lateral transfer (e.g. between primary healthcare [PHC]...

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