Category Archives: Health Systems
New treatment strategies for HIV-positive cancer patients undergoing anticancer medical treatment: Update of the literature
The introduction of highly active antiretroviral therapy (ART) has deeply modified the outcome of HIV patients by improving their overall survival and ameliorating their quality of life (QoL). The prolongation...
Systematic review of alternative HIV preexposure prophylaxis care delivery models to improve preexposure prophylaxis services
Objectives: To identify types, evidence, and study gaps of alternative HIV preexposure prophylaxis (PrEP) care delivery models in the published literature. Design: Systematic review and narrative synthesis. Methods: We searched in the US...
Exploring current nutritional programming and resources available to people living with HIV or AIDS in Canada: A scoping review
OBJECTIVE: The objective of this scoping review is to map the current literature and resources available on nutrition and food programming for people living with HIV and AIDS in Canada....
The effects of cash transfer programmes on HIV/AIDS prevention and care outcomes: A systematic review and meta-analysis of intervention studies
Background: Poverty and social inequality are risk factors for poor health outcomes in patients with HIV/AIDS. In addition to eligibility, cash transfer programmes can be divided into two categories: those with...
The importance of social engagement in the development of an HIV cure: A systematic review of stakeholder perspectives
As research into the development of an HIV cure gains prominence, assessing the perspectives of stakeholders becomes imperative. It empowers stakeholders to determine priorities and influence research processes. We conducted...
Implementation and resource needs for long-acting PrEP in low- and middle-income countries: A scoping review
INTRODUCTION: Several low- and middle-income countries (LMICs) are preparing to introduce long-acting pre-exposure prophylaxis (LAP). Amid multiple pre-exposure prophylaxis (PrEP) options and constrained funding, decision-makers could benefit from systematic implementation...
Cost-effectiveness of anti-retroviral adherence interventions for people living with HIV: A systematic review of decision analytical models
BACKGROUND: Although safe and effective anti-retrovirals (ARVs) are readily available, non-adherence to ARVs is highly prevalent among people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Different adherence-improving interventions have...
Undetectable=Untransmittable=Universal Access (U=U=U): Transforming a foundational, community-led HIV/AIDS health informational advocacy campaign into a global HIV/AIDS health equity strategy and policy priority
BACKGROUND: Undetectable=Untransmittable (U=U) first emerged in 2016 as a health information campaign to promote rigorous scientific evidence that people living with HIV (PLHIV) on effective treatment who have reached an...
Progress towards triple elimination of mother-to-child transmission of HIV, hepatitis B and syphilis in Pacific Island Countries and Territories: A systematic review
The diverse geographic, demographic, and societal factors in the Pacific Island Countries and Territories (PICTs) have contributed to unique epidemiological patterns of HIV, syphilis, and hepatitis B. Transmission can be...
Can peer-based interventions improve adolescent sexual and reproductive health outcomes? An overview of reviews
PURPOSE: An overview of reviews was conducted to summarize the evidence and synthesize the results from systematic reviews. METHODS: The Cochrane and Preferred Reporting Items for Overviews of Reviews reporting...
Systematic review of the values and preferences regarding the use of injectable pre-exposure prophylaxis to prevent HIV acquisition
INTRODUCTION: Pre-exposure prophylaxis (PrEP) is an important HIV prevention option. Two randomized trials have provided efficacy evidence for long-acting injectable cabotegravir (CAB-LA) as PrEP. In considering CAB-LA as an additional...
Perspectives of health workers engaging in task shifting to deliver health care in low-and-middle-income countries: A qualitative evidence synthesis
BACKGROUND: Low- and middle-income countries (LMICs) are experiencing growing demand for healthcare services yet face a persistent shortage in access to specialist health workers (SHWs). Task shifting is an approach...
