Category Archives: Health Systems
Cutting edge strategies for screening of novel anti-HIV drug candidates against HIV infection: A concise overview of cell based assays
The advent of Highly Active Antiretroviral Therapy has majorly contributed towards reducing the morbidity and mortality associated with HIV infected people, thus improving the quality of their life. Still, the...
New treatment strategies for HIV-positive cancer patients undergoing anticancer medical treatment: Update of the literature
The introduction of highly active antiretroviral therapy (ART) has deeply modified the outcome of HIV patients by improving their overall survival and ameliorating their quality of life (QoL). The prolongation...
The importance of social engagement in the development of an HIV cure: A systematic review of stakeholder perspectives
As research into the development of an HIV cure gains prominence, assessing the perspectives of stakeholders becomes imperative. It empowers stakeholders to determine priorities and influence research processes. We conducted...
The effects of cash transfer programmes on HIV/AIDS prevention and care outcomes: A systematic review and meta-analysis of intervention studies
Background: Poverty and social inequality are risk factors for poor health outcomes in patients with HIV/AIDS. In addition to eligibility, cash transfer programmes can be divided into two categories: those with...
Can peer-based interventions improve adolescent sexual and reproductive health outcomes? An overview of reviews
PURPOSE: An overview of reviews was conducted to summarize the evidence and synthesize the results from systematic reviews. METHODS: The Cochrane and Preferred Reporting Items for Overviews of Reviews reporting...
Systematic review of the values and preferences regarding the use of injectable pre-exposure prophylaxis to prevent HIV acquisition
INTRODUCTION: Pre-exposure prophylaxis (PrEP) is an important HIV prevention option. Two randomized trials have provided efficacy evidence for long-acting injectable cabotegravir (CAB-LA) as PrEP. In considering CAB-LA as an additional...
Perspectives of health workers engaging in task shifting to deliver health care in low-and-middle-income countries: A qualitative evidence synthesis
BACKGROUND: Low- and middle-income countries (LMICs) are experiencing growing demand for healthcare services yet face a persistent shortage in access to specialist health workers (SHWs). Task shifting is an approach...
Understanding geriatric models of care for older adults living with HIV: A scoping review and qualitative analysis
BACKGROUND: Advances in Human Immunodeficiency Virus (HIV) treatment have reduced mortality rates and consequently increased the number of individuals with HIV living into older age. Despite this, people aged 50Aÿyears...
The impact of multiple-behavior HIV interventions as a function of regional disadvantages: An analysis of syndemics
OBJECTIVE: Disadvantaged populations, including inhabitants of developing countries as well as racial/ethnic and sexual minorities in the United States, are disproportionally burdened by human immunodeficiency virus (HIV) infection, delayed HIV...
Implementation and resource needs for long-acting PrEP in low- and middle-income countries: A scoping review
INTRODUCTION: Several low- and middle-income countries (LMICs) are preparing to introduce long-acting pre-exposure prophylaxis (LAP). Amid multiple pre-exposure prophylaxis (PrEP) options and constrained funding, decision-makers could benefit from systematic implementation...
Cost-effectiveness of anti-retroviral adherence interventions for people living with HIV: A systematic review of decision analytical models
BACKGROUND: Although safe and effective anti-retrovirals (ARVs) are readily available, non-adherence to ARVs is highly prevalent among people living with human immunodeficiency virus/acquired immunodeficiency syndrome (PLWHA). Different adherence-improving interventions have...
