Category Archives: Health Systems
HIV vulnerability among adolescent girls and young women in sub-Saharan Africa: A systematic review of individual social and structural determinants
BACKGROUND: Adolescent girls and young women (AGYW) aged 15 to 24 years continue to bear a disproportionate burden of HIV infections in sub-Saharan Africa. Although substantial research has examined behavioral...
Integrating smoking cessation into HIV care settings: A systematic review and meta-analysis of effectiveness and the evidence gap in cost-effectiveness
The prevalence of smoking among people living with HIV (PLWH) is higher than in the general population, and PLWH who smoke are at increased risk of both smoking- and HIV-related...
Exercise as a preventive and therapeutic strategy for non-communicable diseases in people living with HIV: Evidence, mechanisms and clinical implications
Objective To synthesise evidence on exercise for preventing and managing non-communicable diseases (NCDs) among HIV clients, emphasising sub-Saharan Africa. Design Narrative review. Data sources Meta-analyses, randomised trials, cohort studies, mechanistic...
Integrated care models for HIV, diabetes and hypertension in sub-Saharan Africa: A systematic review of effectiveness, implementation and real-world applicability
Background Sub-Saharan Africa faces a syndemic of HIV and non-communicable diseases (NCDs), particularly diabetes and hypertension. Integrated care models have been promoted to improve service efficiency and patient outcomes; however,...
Oral health education interventions for people living with HIV: A scoping review of delivery approaches and reported outcomes
Background People living with HIV (PLWH) experience a high burden of oral diseases that can impair daily function and affect adherence to HIV care. Oral health education has the potential...
Prevalence of hypertension, diabetes, obesity, and high cholesterol among older people living with HIV: A systematic review and meta-analysis
INTRODUCTION: Metabolic comorbidities are significant health challenges for older people living with HIV (PLHIV). This systematic review and meta-analysis aimed to synthesize existing evidence and provide the pooled prevalence of...
What tools do we have to end the US HIV epidemic? A review of structural, biomedical and implementation interventions and their potential population impact
INTRODUCTION: The United States Ending the HIV Epidemic (EHE) initiative was always challenged by structural and implementation barriers to HIV care. On top of that, since 2025, there are additional...
Assessing the impact, barriers and facilitators of peer-driven interventions on the prevention of mother-to-child transmission of HIV in low- and middle-income countries: A systematic review and meta-analysis
Introduction: Peer interventions may improve retention across the prevention of mother-to-child transmission (PMTCT) cascade in low- and middle-income countries (LMICs), where poor adherence to antiretroviral therapy (ART) remains a major barrier....
Breastfeeding practices and perspectives in the setting of maternal HIV in high-income countries since the shift in the United States national guidelines: A scoping review
Introduction: United States national guidelines around infant feeding in the setting of maternal HIV were updated significantly in 2023. The updated guidelines encourage evidence-based counseling and emphasize shared decision-making around infant...
Assessment of knowledge and use of HIV primary and secondary prevention strategies in Portugal: A scoping review
BACKGROUND: Portugal has been committed to achieve UNAIDS target goals by the end of 2030 by improving accessibility of prevention programs to the general population and key populations. However, Portugal...
The role of religion and spirituality in HIV prevention: A systematic literature review and network analysis
Religion and spirituality play an important role in shaping attitudes, beliefs, social norms, and preventive behaviors related to Human Immunodeficiency Virus (HIV) prevention across diverse populations and cultural settings. This...
Mapping psychosocial interventions for mental health and well-being among pregnant women living with HIV: A scoping review
BACKGROUND: Pregnant women living with HIV are at increased risk of depression, anxiety, stigma, gender-based violence, and poor engagement in prevention of mother-to-child transmission services. Psychosocial interventions are increasingly used...
