Category Archives: Health Systems
State of HIV research in Venezuela: A systematic review
BACKGROUND: Venezuela’s recent economic and political instability has severely compromised its healthcare infrastructure, impacting the management of infectious diseases, including human immunodeficiency virus (HIV). This disruption hinders progress towards the...
HIV-related mortality time trends among children and young adolescents on antiretroviral therapy by age, treatment duration, and region: A systematic review and meta-regression analysis
Background: Past cohort studies have examined mortality among children and young adolescents (aged 0–14 years) who have received antiretroviral therapy (ART), but no systematic reviews have been undertaken to synthesise these...
HIV status and the risk of typhoid fever and iNTS: A systematic review and meta-analysis
OBJECTIVES: The WHO recommends prioritising people living with HIV (PLHIV) for typhoid vaccination, but evidence for increased typhoid fever risk is inconsistent. We aimed to evaluate whether HIV infection alters...
Guidelines for the transfer of people living with HIV attending primary healthcare facilities in South Africa: A scoping review
People living with HIV may move between health facilities: this is called ‘transfer’, and includes up- and down-referral based on clinical condition and lateral transfer (e.g. between primary healthcare [PHC]...
Risk perception of human immunodeficiency virus, acquired immune deficiency syndrome, and reproductive health education among among junior and senior high school students: A scoping review
This scoping review aims to identify studies that examine the existence and impact of HIV/AIDs education among high school-aged individuals in Ghana, underscoring the association of factors such as stigma...
Patient-reported outcomes in clinical trials assessing the effectiveness of cabotegravir + rilpivirine long-acting injections as antiretroviral therapy: A systematic review
Introduction: Human immunodeficiency virus-1 (HIV-1) continues to have ahigh global burden, with approximately 39.9 million people currently livingwith the virus. Despite the clinical success of antiretroviral therapy (ART),adherence remains a...
Implementation of trauma-informed care into clinical HIV prevention and care settings: A decade of limited progress
PURPOSE OF THE REVIEW: Trauma is common among people living with or at risk for HIV and associated with increased HIV risk and worse HIV care outcomes. Trauma-informed care (TIC)...
Mobile health intervention tools promoting HIV pre-exposure prophylaxis among adolescent girls and young women in sub-Saharan Africa: Scoping review
BACKGROUND: In 2022, 3100 adolescent girls and young women in sub-Saharan Africa experienced new HIV infections each week. HIV pre-exposure prophylaxis (PrEP) is effective at preventing HIV but has limited...
Cost-effectiveness analyses of adolescent- and young-adult-focused HIV interventions incorporating HIV transmission: A scoping review of modeling methods and proposed guidance
BACKGROUND: Adolescents and young adults (AYA) are disproportionately affected by human immunodeficiency virus (HIV) globally, with high-burden population subgroups differing across regions. Cost-effectiveness modeling analyses of AYA-focused HIV interventions have...
