Category Archives: Health Systems

Barriers and facilitators of rendering HIV services by community health workers in sub-Saharan Africa: A meta-synthesis

2021

OBJECTIVES: To synthesise qualitative studies that address the barriers to and facilitators of providing HIV services by community health workers (CHWs) in sub-Saharan Africa (SSA). DESIGN: This meta-synthesis was guided...

HIV self-testing with digital supports as the new paradigm: A systematic review of global evidence (2010–2021)

2021

BACKGROUND: HIV self-testing (HIVST) is recommended by the WHO as an innovative strategy to reach UNAIDS targets to end HIV by 2030. HIVST with digital supports is defined as the...

Experience of chronic noncommunicable disease in people living with HIV: A systematic review and meta-aggregation of qualitative studies

2021

BACKGROUND: An increasing number of people living with HIV (PLWH) have had chronic noncommunicable diseases (NCDs) over the last 5 years. However, robust evidence regarding the perception and challenges of...

Adolescents and age of consent to HIV testing: An updated review of national policies in sub-Saharan Africa

2021

Objectives In sub-Saharan Africa (SSA) where HIV burden is highest, access to testing, a key entry point for prevention and treatment, remains low for adolescents (aged 10–19). Access may be hampered...

A systematic review of neighborhood-level influences on HIV vulnerability

2021

A better understanding of the social-structural factors that influence HIV vulnerability is crucial to achieve the goal of ending the HIV epidemic by 2030. Given the role of neighborhoods in...

TLR-agonist mediated enhancement of antibody-dependent effector functions as strategy for an HIV-1 cure

2021

BACKGROUND: The current treatment for HIV-1 is based on blocking various stages in the viral replication cycle using combination antiretroviral therapy (ART). Even though ART effectively controls the infection, it...

Health programmes and services addressing the prevention and management of infectious diseases in people who inject drugs in Canada: A systematic integrative review

2021

OBJECTIVES: People who inject drugs (PWID) experience a high burden of injection drug use-related infectious disease and challenges in accessing adequate care. This study sought to identify programmes and services...

HIV-proteins-associated CNS neurotoxicity, their mediators, and alternative treatments

2021

Human immunodeficiency virus (HIV)-infected people’s livelihoods are gradually being prolonged with the use of combined antiretroviral therapy (ART). Conversely, despite viral suppression by ART, the symptoms of HIV-associated neurocognitive disorder...

HIV care continuum interventions for Black men who have sex with men in the USA

2021

Disparities persist along the HIV care continuum among Black men who have sex with men (MSM) in the USA. As part of an initiative funded by the Health Resources and...

HIV care outcomes among transgender persons with HIV infection in the united states: A systematic review and meta-analysis, 2006–2021

2021

Objectives: HIV prevalence is an estimated 14% among transgender women (TW) and 3% among transgender men (TM). HIV care is vital for viral suppression but is hindered by transphobia and HIV...

Post-immigration factors affecting retention in HIV care and viral suppression in Latin American and Caribbean immigrant populations in the United States: A systematic review

2021

Objectives: To reduce disparities in HIV care outcomes among Latin American and Caribbean (LAC) immigrants living with HIV in the U.S., it is necessary to identify factors influencing HIV care in...

Pharmacy-based interventions to increase use of HIV pre-exposure prophylaxis in the United States: A scoping review

2021

HIV pre-exposure prophylaxis (PrEP) remains underutilized in the U.S. Since greater than 85% of PrEP prescriptions are filled at commercial pharmacies, pharmacists are uniquely positioned to increase PrEP use. This...

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