Category Archives: Health Systems
Understanding the implementation of patient navigation for adults living with HIV: A scoping review of components, equity considerations and lessons learned
Background People living with HIV navigate complex medical and social challenges that impact engagement in care, including stigma, poverty and systemic inequities. Patient navigation has emerged as a promising approach...
The global epidemiology of injecting drug use, HIV, viral hepatitis and tuberculosis among people who are incarcerated: A multistage systematic review
Background: This global systematic review assesses the prevalence of injecting drug use (IDU) and key infectious diseases (HIV, hepatitis C virus [HCV], tuberculosis and hepatitis B virus [HBV]) among people...
Patients’ perspectives on medication adherence feedback interventions for managing long-term medications: A systematic review of qualitative evidence
INTRODUCTION: Optimising medication usage is a worldwide challenge. While numerous feedback interventions have been developed to address this issue, understanding patients’ perspectives on the use of such interventions to optimise...
International guidelines for the management of healthcare workers living with HIV: A systematic comparative review
BACKGROUND: Despite strong evidence that sustained HIV viral suppression eliminates transmission risk (“undetectable equals untransmittable”, U=U), national approaches to managing healthcare workers (HCWs) living with HIV remain heterogeneous. Because such...
Unmet need for family planning among reproductive-age women living with HIV in Africa: A systematic review and meta-analysis
Background Unmet need for family planning remains a major challenge worldwide, particularly in Africa, contributing to unintended pregnancies, unsafe abortions, and increased maternal morbidity and mortality. Reducing the unmet need...
Implementation of point of care HIV viral load monitoring for people living with HIV in low- and middle-income countries: A systematic review on implementation research outcomes
BACKGROUND: Viral load monitoring has rapidly increased among people living with HIV(PLHIV) in low- and middle-income countries (LMICs), resulting in an increased laboratory workload. The use of innovative Point of...
Effectiveness of pre-exposure prophylaxis (PrEP) in the prevention of human immunodeficiency virus (HIV): A systematic review of randomized controlled trials with narrative synthesis
Human immunodeficiency virus (HIV) prevention has advanced substantially, yet ending new transmissions by 2030 remains uncertain. Pre-exposure prophylaxis (PrEP) has high biological efficacy, but real-world effectiveness varies due to adherence,...
Leveraging the barriers and facilitators of pre-exposure prophylaxis (PrEP) care among Latino men who have sex with men in the U.S. to inform intervention: A systematic literature review (2018–2023)
HIV disproportionately affects Latino men who have sex with men (LMSM) in the United States (U.S.). Pre-exposure prophylaxis (PrEP) reduces HIV transmission, but prescription and use rates remain low among...
Experiences and outcomes of peer navigation and support interventions for adolescents on HIV treatment in sub-Saharan Africa: A qualitative evidence synthesis
Adolescents living with HIV (ALHIV) face ongoing challenges with treatment adherence and engagement in care, resulting in lower viral suppression rates compared to adults. Peer navigation has shown promise in...
Effectiveness of mobile health (mHealth) interventions on ART adherence among people living with HIV in low- and middle-income countries: A systematic review and meta-analysis
Antiretroviral therapy (ART) is essential for HIV treatment, yet maintaining high adherence remains challenging in resource-limited settings. Mobile health (mHealth) interventions offer a scalable approach to support adherence. This meta-analysis...
Worldwide changes in HIV-related stigma among people living with HIV: A cross-temporal meta-analysis and systematic review
Background: HIV-related stigma among people living with HIV has emerged as a growing public health concern, yet limited longitudinal data are available to characterize its evolution over time. In this study,...
