Category Archives: Health Systems
Adherence to methadone maintenance treatment and antiretroviral therapy
Key take-home messages HIV-positive intravenous drug users (IDUs) are at greater risk of non-adherence to highly active antiretroviral therapy (HAART) compared to the general HIV population. Psychological problems, active drug...
Effectiveness and cost-effectiveness of pre- & post-exposure prophylaxis for HIV
Key take-home messages There is not enough evidence to draw conclusions about the clinical effectiveness of non-occupational post-exposure prophylaxis (PEP); however, non-occupational PEP is possibly a cost-effective intervention. PEP has...
The effectiveness and cost-effectiveness of screening for HIV in migrants in the EU/EEA: A systematic review
Migrants, defined as individuals who move from their country of origin to another, account for 40% of newly-diagnosed cases of human immunodeficiency virus (HIV) in the European Union/European Economic Area...
Use of antiretroviral therapy during pregnancy and adverse birth outcomes among women living with HIV-1 in low- and middle-income countries: A systematic review
BACKGROUND: Worldwide, nearly 18 million women of reproductive age are living with HIV-1. Although increased access to antiretroviral therapy (ART) during pregnancy has significantly reduced HIV-1 mother-to-child transmission (MTCT), a...
Integrated models of care for individuals with opioid use disorder: How do we prevent HIV and HCV?
PURPOSE OF REVIEW: To describe models of integrated and co-located care for opioid use disorder (OUD), hepatitis C (HCV), and HIV. RECENT FINDINGS: The design and scale-up of multidisciplinary care...
Effectiveness of depression interventions for people living with HIV in Sub-Saharan Africa: A systematic review & meta-analysis of psychological & immunological outcomes
This meta-analytic review evaluated the effectiveness of depression interventions on the psychological and immunological outcomes of people living with HIV in sub-Saharan Africa. 14 studies, yielding 932 participants were eligible....
Analytical quality and effectiveness of point-of-care testing in community pharmacies: A systematic literature review
BACKGROUND: Point-of-care tests are characterised through the ability of conducting them near the patient’s side without the necessity of a laboratory. They can be applied in different healthcare settings to...
The cascade of care following community-based detection of HIV in sub-Saharan Africa – A systematic review with 90-90-90 targets in sight
INTRODUCTION: We aimed to establish how effective community-based HIV testing services (HTS), including home and community location based (non-health facility) HIV testing services (HB-/CLB-HTS), are in improving care in sub-Saharan...
