Category Archives: Health Systems

High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: An analysis of 715 cases from Malawi

2013

Mortality from bacterial meningitis in African adults is significantly higher than those in better resourced settings and adjunctive therapeutic interventions such as dexamethasone and glycerol have been shown to be...

HIV prevention, treatment, and care services for people who inject drugs: A systematic review of global, regional, and national coverage

2010

Background: Previous reviews have examined the existence of HIV prevention, treatment, and care services for injecting drug users (IDUs) worldwide, but they did not quantify the scale of coverage. We...

AIDS in Latin America: Assessing the current status of the epidemic and the ongoing response

2008

Background: This article provides a summary of the current status of the HIV/AIDS epidemic in Latin America, as well as an outline of the diverse responses to it. Methods: A...

Geographical representativeness of published and ongoing randomized controlled trials. The example of: Tobacco consumption and HIV infection

2011

Background: The challenge for evidence-based healthcare is to reduce mortality and the burden of diseases. This study aimed to compare where research is conducted to where research is needed for...

Health sector demand-side financial incentives in low- and middle-income countries: A systematic review on demand- and supply-side effects

2014

Demand-side financial incentive (DSF) is an emerging strategy to improve health seeking behavior and health status in many low- and middle-income countries. This narrative synthesis assessed the demand- and supply-side...

Diagnostic tests in HIV management: A review of clinical and laboratory strategies to monitor HIV-infected individuals in developing countries

2006

We conducted a systematic review on the performance of diagnostic tests for clinical and laboratory monitoring of HIV-infected adults in developing countries. Diagnostic test information collected from computerized databases, bibliographies...

What works to meet the sexual and reproductive health needs of women living with HIV/AIDS

2011

It is critical to include a sexual and reproductive health lens in HIV programming as most HIV transmission occurs through sexual intercourse. As global attention is focusing on the sexual...

Treatment outcomes from community-based drug resistant tuberculosis treatment programs: A systematic review and meta-analysis

2014

BACKGROUND: There is increasing evidence that community-based treatment of drug resistant tuberculosis (DRTB) is a feasible and cost-effective alternative to centralized, hospital-based care. Although several large programs have reported favourable...

Task shifting for the delivery of pediatric antiretroviral treatment: A systematic review

2014

BACKGROUND: Pediatric antiretroviral treatment coverage in resource-limited settings continues to lag behind adults. Task shifting is an effective approach broadly used for adults, which some countries have also adopted for...

The contribution of the HIV specialist nurse to HIV care: A scoping review

2013

AIMS AND OBJECTIVES: To systematically identify and critically examine the evidence of the contribution of the HIV nurse specialist to provision of HIV care in the UK and other developed...

Strategies for integrating primary health services in low- and middle-income countries at the point of delivery

2011

BACKGROUND: In some low- and middle-income countries, separate vertical programmes deliver specific life-saving interventions but can fragment services. Strategies to integrate services aim to bring together inputs, organisation, and delivery...

Factors mediating HIV risk among female sex workers in Europe: A systematic review and ecological analysis

2013

OBJECTIVES: We reviewed the epidemiology of HIV and selected sexually transmitted infections (STIs) among female sex workers (FSWs) in WHO-defined Europe. There were three objectives: (1) to assess the prevalence...

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