Category Archives: Health Systems

Pre-exposure prophylaxis of HIV: A right way to go or a long way to go?

2016

Antiretroviral drugs are being tried as candidates for the pre-exposure prophylaxis (PrEP) against HIV for a considerable period, due to their potential for immediate inhibition of viral replication. Discrepancies in...

Revitalizing the HIV response in Pakistan: A systematic review and policy implications

2014

BACKGROUND: We sought to describe the epidemiology of HIV in Pakistan and prioritize interventions to improve the effectiveness and efficiency of the response to HIV. METHODS: We conducted a systematic...

The cost and cost-effectiveness of gender-responsive interventions for HIV: A systematic review

2014

INTRODUCTION: Harmful gender norms and inequalities, including gender-based violence, are important structural barriers to effective HIV programming. We assess current evidence on what forms of gender-responsive intervention may enhance the...

The cost and impact of scaling up pre-exposure prophylaxis for HIV prevention: A systematic review of cost-effectiveness modelling studies

2013

BACKGROUND: Cost-effectiveness studies inform resource allocation, strategy, and policy development. However, due to their complexity, dependence on assumptions made, and inherent uncertainty, synthesising, and generalising the results can be difficult....

Factors impacting HIV testing: A review – perspectives from Australia, Canada, and the UK

2015

With the current global focus on strengthening HIV prevention through greater testing and treatment uptake, it is increasingly salient to identify and address barriers to testing. A review of the...

Factors influencing the implementation of chronic care models: A systematic literature review

2015

BACKGROUND: The increasing prevalence of chronic disease faced by both developed and developing countries is of considerable concern to a number of international organisations. Many of the interventions to address...

Socio-cultural factors influencing the prevention of mother-to-child transmission of HIV in Nigeria: A synthesis of the literature

2014

BACKGROUND: Currently, Nigeria alone accounts for 30% of the burden of mother-to-child transmission of HIV. This review explores the socio-cultural factors influencing prevention of mother-to-child transmission of HIV (PMTCT) service...

HIV pre-test information, discussion or counselling? A review of guidance relevant to the WHO European Region

2016

OBJECTIVES: In the context of a shift from exceptionalism to normalisation, this study examines recommendations/evidence in current pan-European/global guidelines regarding pre-test HIV testing and counselling practices in health care settings....

A systematic review on cost effectiveness of HIV prevention interventions in the United States

2015

BACKGROUND: The Centers for Disease Control and Prevention (CDC) focus on funding HIV prevention interventions likely to have high impact on the HIV epidemic. In its most recent funding announcement...

Scarcity of protective items against HIV and other bloodborne infections in 13 low- and middle-income countries

2014

OBJECTIVE: To assess protection of surgical healthcare workers against HIV and other bloodborne infections in low- and middle-income countries (LMICs). METHODS: Literature review based on recent studies assessing baseline surgical...

Trends in task shifting in HIV treatment in Africa: Effectiveness, challenges and acceptability to the health professions

2015

BACKGROUND: Task shifting has been suggested to meet the demand for initiating and managing more patients on antiretroviral therapy. Although the idea of task shifting is not new, it acquires...

Regional and national guideline recommendations for digital ano-rectal examination as a means for anal cancer screening in HIV positive men who have sex with men: A systematic review

2014

BACKGROUND: Although anal cancer is common in HIV positive men who have sex with men, few centres offer systematic screening. Regular digital ano-rectal examination (DARE) is a type of screening...

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