Category Archives: Health Systems

Characterizing the HIV care continuum among children and adolescents with HIV in eastern and southern Africa in the era of “Universal Test and Treat”: A systematic review and meta-analysis

2025

INTRODUCTION: The “Universal Test and Treat” (UTT) era for antiretroviral therapy (ART) increased HIV service delivery to children and adolescents aged 0-19 with HIV. The goal is to reach ƒ%95%...

The effectiveness of monetary incentives in improving viral suppression, treatment adherence, and retention in care among the general population of people living with HIV: A systematic review and meta-analysis

2025

Background Achieving and maintaining viral suppression and optimal adherence to antiretroviral therapy are crucial for improving health outcomes in general population of people living with HIV. This study aimed to...

Impact of mHealth on enhancing pre-exposure prophylaxis adherence and strengthening the HIV prevention cascade among key populations: A systematic review and meta-analysis

2025

Background Good adherence to pre-exposure prophylaxis (PrEP) is critical for effective HIV prevention. Despite the growing awareness of PrEP, many individuals remain at a preliminary understanding stage and struggle to...

Effect of human immunodeficiency virus self-testing (HIVST) on HIV and STI testing uptake among men who have sex with men (MSM): A systematic review and meta-analysis of randomized controlled trials

2025

Objectives: The objective of this review was to assess the effectiveness of HIVST in terms of increasing HIV testing, early detection of HIV, and sexually transmitted infections among MSM via...

A meta-analysis of prevalence and moderating factors of malnutrition among people living with HIV across countries

2025

Malnutrition is a critical issue for people living with HIV (PLWH), affecting their immune function, health outcomes, and response to antiretroviral therapy. This meta-analysis assessed the prevalence of malnutrition among...

The key design features and effectiveness of social network interventions for HIV testing and linkage services in low- and middle-income countries: A systematic review and meta-analysis

2025

INTRODUCTION: HIV remains a global health challenge with a reported 39 million people living with HIV (PLHIV) in 2022. Sub-Saharan Africa, Asia and the Pacific are home to 82% of...

Effects of nutritional interventions on nutritional and immunological status and adherence to antiretroviral treatment among adults living with HIV in low- and middle-income countries: Systematic review and meta-analysis

2025

Background HIV/AIDS may cause malnutrition, both directly and indirectly, through common infections. This systematic review and meta-analysis aim to evaluate the effects of nutritional interventions on nutritional status, immunological status,...

Health educational interventions for adolescents living with HIV: A scoping review

2025

BACKGROUND: Adolescents living with HIV face unique challenges as they gain greater independence while transitioning into adulthood. They must adjust their self-management activities and take primary responsibility for their health,...

Global health initiatives and the combat of HIV/AIDS on the African continent: A scoping review

2025

The aim is to identify, in the literature, the influence of Global Health Initiatives (GHI) on the HIV combat in Africa. A scoping review was carried out in March 2023...

Technologies for healthy lifestyle in people with HIV: A systematic review

2025

OBJECTIVE: to analyze clinical trials that assessed the effectiveness of technologies for healthy lifestyles in people with HIV. METHOD: A systematic review, conducted in five databases, with association of controlled...

Harms associated with injecting in public spaces: A global systematic review and meta-analysis

2025

BACKGROUND: Despite increasing backlash against harm reduction efforts and the need to understand the risk environments encountered by people who inject drugs (PWID), a quantitative systematic review on public injecting...

Evaluating predictive performance, validity, and applicability of machine learning models for predicting HIV treatment interruption: A systematic review

2025

Background HIV treatment interruption remains a significant barrier to achieving global HIV/AIDS control goals. Machine learning (ML) models offer potential for predicting treatment interruption by leveraging large clinical data. Understanding...

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