Category Archives: Health Systems

Loneliness and social isolation in people with HIV

2025

PURPOSE OF REVIEW: Antiretroviral therapy (ART) has significantly extended the life expectancy of people with HIV (PWH). However, as this population ages, they face increased risk of social isolation and...

Climate change and extreme weather events and linkages with HIV outcomes: Recent advances and ways forward

2025

PURPOSE OF REVIEW: Discuss the recent evidence on climate change and related extreme weather events (EWE) and linkages with HIV prevention and care outcomes. RECENT FINDINGS: We identified 22 studies...

HIV pre-exposure prophylaxis (PrEP) use among PrEP-eligible men who have sex with men: A systematic review and meta-analysis

2025

Objective: Scaling up pre-exposure prophylaxis (PrEP) is critical to combating the AIDS epidemic, especially among PrEP-eligible men who have sex with men (MSM). This study summarizes the global proportion of PrEP-eligible...

Retention in care after transition to adult care for adolescents and young adults with HIV: A systematic review and meta-analysis

2025

Objective: To evaluate the retention rates of adolescents and young adults (aged 10-25 years) living with HIV during the transition to adult HIV care. Methods: The study involved 15 cohort studies conducted...

Incidence of adverse drug reactions among HIV patients on antiretroviral drugs in Ethiopia: A systematic review and meta-analysis

2025

Introduction: In recent decades, AIDS–related illnesses have declined due to the widespread use of highly active antiretroviral therapy (HAART). Despite the numerous benefits that HAART provides, it causes significant challenges for...

Prevalence of Mpox vaccine acceptance and hesitancy among people living with HIV: A comprehensive systematic review and meta-analysis

2025

Background Vaccine acceptance among People Living with HIV (PLWH) is crucial for managing and mitigating the spread of infectious diseases, including Mpox. This systematic review and meta-analysis assess the rate...

Efficacy of long-acting cabotegravir plus rilpivirine in viraemic people living with HIV: A systematic review and meta-analysis

2025

BACKGROUND: Long-acting cabotegravir/rilpivirine (LA-CAB/RPV) is currently approved as a switch strategy in people living with HIV virally suppressed on oral antiretroviral therapy. Although small reports on specific, difficult-to-treat populations demonstrated...

HIV risk score and prediction model in the United States: A scoping review

2025

Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors...

Burden of depression among HIV caregivers in India: A systematic review and meta-analysis

2025

Caregivers of individuals living with HIV face significant mental health challenges, with depression being the most common. Despite global research highlighting this burden, studies specific to the Indian context are...

Evidence on digital HIV self-testing from accuracy to impact: Updated systematic review

2025

BACKGROUND: HIV self-testing has gained momentum following the approval of self-testing methods and novel technological advancements. Digital HIV self-testing involves completing an oral or blood-based HIV self-test with support from...

Global prevalence of advanced HIV disease in healthcare settings: A rapid review

2025

Introduction Recent studies have indicated a high enduring burden of advanced HIV disease, but estimates across regions and settings are lacking. The aim of this study was to estimate the...

The impact of place of residence on antiretroviral therapy adherence: A systematic review and meta-analysis

2025

Objective: There is evidence of geographical variation in HIV coverage and antiretroviral therapy (ART) adherence, and studies have investigated how the place of residence of people living with HIV (PLWH) influences...

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