Category Archives: Health Systems

Equity in utilization of antiretroviral therapy for HIV-infected people in South Africa: A systematic review

2014

INTRODUCTION: About half a million people in South Africa are deprived of antiretroviral therapy (ART), and there is little systematic knowledge on who they are – e.g. by severity of...

The cost and cost-effectiveness of gender-responsive interventions for HIV: A systematic review

2014

INTRODUCTION: Harmful gender norms and inequalities, including gender-based violence, are important structural barriers to effective HIV programming. We assess current evidence on what forms of gender-responsive intervention may enhance the...

The cost and impact of scaling up pre-exposure prophylaxis for HIV prevention: A systematic review of cost-effectiveness modelling studies

2013

BACKGROUND: Cost-effectiveness studies inform resource allocation, strategy, and policy development. However, due to their complexity, dependence on assumptions made, and inherent uncertainty, synthesising, and generalising the results can be difficult....

Global burden of transmitted HIV drug resistance and HIV-exposure categories: A systematic review and meta-analysis

2014

OBJECTIVES: Our aim was to review the global disparities of transmitted HIV drug resistance (TDR) in antiretroviral-naive MSM, people who inject drugs (PWID) and heterosexual populations in both high-income and...

Barriers to implementation of rapid and point-of-care tests for human immunodeficiency virus infection: Findings from a systematic review (1996–2014)

2015

Implementation of human immunodeficiency virus rapid and point-of-care tests (RDT/POCT) is understood to be impeded by many different factors that operate at 4 main levels-test devices, patients, providers, and health...

Pre-exposure prophylaxis of HIV: A right way to go or a long way to go?

2016

Antiretroviral drugs are being tried as candidates for the pre-exposure prophylaxis (PrEP) against HIV for a considerable period, due to their potential for immediate inhibition of viral replication. Discrepancies in...

A systematic review on cost effectiveness of HIV prevention interventions in the United States

2015

BACKGROUND: The Centers for Disease Control and Prevention (CDC) focus on funding HIV prevention interventions likely to have high impact on the HIV epidemic. In its most recent funding announcement...

Factors impacting HIV testing: A review – perspectives from Australia, Canada, and the UK

2015

With the current global focus on strengthening HIV prevention through greater testing and treatment uptake, it is increasingly salient to identify and address barriers to testing. A review of the...

Factors influencing the implementation of chronic care models: A systematic literature review

2015

BACKGROUND: The increasing prevalence of chronic disease faced by both developed and developing countries is of considerable concern to a number of international organisations. Many of the interventions to address...

Socio-cultural factors influencing the prevention of mother-to-child transmission of HIV in Nigeria: A synthesis of the literature

2014

BACKGROUND: Currently, Nigeria alone accounts for 30% of the burden of mother-to-child transmission of HIV. This review explores the socio-cultural factors influencing prevention of mother-to-child transmission of HIV (PMTCT) service...

The proportion and trend of human immunodeficiency virus infections associated with men who have sex with men from Chinese voluntary blood donors: A systematic review and meta-analysis

2015

BACKGROUND: Human immunodeficiency virus (HIV)-positive cases associated with men who have sex with men (MSM) have rapidly increased over the past years. The objective of this study is to comprehensively...

The impact of social services interventions in developing countries: A review of the evidence of impact on clinical outcomes in people living with HIV

2015

BACKGROUND: Social service interventions have been implemented in many countries to help people living with HIV (PLHIV) and household members cope with economic burden as a result of reduced earning...

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