Category Archives: Delivery arrangements
How care is organized
Viral load suppression after enhanced adherence counseling among HIV patients on antiretroviral therapy (2019–2024): A systematic review and meta-analysis in East Africa
Introduction Viral load suppression is essential for reducing human immunodeficiency virus (HIV) related morbidity and mortality. To eliminate the HIV epidemic and enhance adherence to antiretroviral therapy (ART) globally, the...
Unveiling the underestimated prevalence of HIV, HBV and TB triple infection in Asia, South America, and Africa: A systematic review and meta-analysis
BACKGROUND: Human immunodeficiency virus (HIV) is a genus of retroviruses that targets immune cells and may eventually cause immune-deficiency illness. Triple infection of HIV/hepatitis B virus (HBV) /tuberculosis (TB) leads...
The effect of Chinese medicine therapeutics on HIV/AIDS: A systematic review and network meta-analysis
Background Although antiretroviral therapy (ART) effectively suppresses HIV, incomplete immune reconstitution affects 20%–30% of adherent patients. Chinese Medicine (CM) demonstrates potential as a complementary therapy for human immunodeficiency virus (HIV)/acquired...
Influences of gender-based stigma on HIV prevention and care among older women: A scoping review
Older women living with HIV are uniquely situated at multiple marginalized intersections because of their gender, age, and HIV status. However, research into how gender-based stigma (GBS) affects HIV prevention...
HIV self-testing and partner notification strategies for key populations in low- to upper-middle-income countries: A mixed-methods systematic review
BACKGROUND: HIV self-testing (HIVST) enhances case diagnosis, but information on its integration for index testing to partner notification is limited. Assessing the acceptability and feasibility of index HIVST and partner...
Effect of same-day HIV treatment initiation (SDI) on 1-year outcomes in low- and middle-income countries: Systematic review and meta-analysis of randomised trials
Introduction Same-day initiation (SDI) of antiretroviral therapy is recommended for people presenting with HIV who have no contraindications. We reviewed the evidence on SDI interventions in low- and middle-income countries...
Risk of hepatitis C virus reinfection after direct-acting antiviral treatment among HIV-positive men who have sex with men and people who inject drugs: A systematic review and meta-analysis
The incidence of hepatitis C virus (HCV) reinfection following successful direct-acting antiviral therapy in HIV/HCV co-infected individuals remains a significant public health concern. This study aimed to estimate the reinfection...
Evolving landscape of economic evaluations of HIV pre-exposure prophylaxis and pre-exposure prophylaxis implementation strategies: A systematic review
INTRODUCTION: Economic evaluations of HIV pre-exposure prophylaxis (PrEP) and associated implementation strategies guide evidence-based policies, programmes and resource allocation. Since 2015, there has been an evolution in PrEP modalities, implementation...
Interest in and preference for long-acting injectable pre-exposure prophylaxis among men who have sex with men, trans* individuals, and cisgender heterosexual women: A global systematic review and meta-analysis
BACKGROUND: Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) offers potentials for expanding PrEP coverage and improving public health outcomes. This study synthesizes evidence on the prevalence and determinants of interest in and...
Recent advances in nanoparticle-based antiretroviral drug delivery systems for HIV treatment and prevention: A comprehensive review
BACKGROUND: AIDS disease, caused by HIV, is a highly prevalent disease disturbing global health and swaying economic progress and social fidelity in the world. PURPOSE: Eradication and cure of HIV...
Prevalence and determinants of virologic failure among HIV patients on ART in Africa: A systematic review and meta-analysis
Background The Joint United Nations Programme on HIV/AIDS (UNAIDS) has established the 95-95-95 targets, aiming that by 2030, 95% of individuals on ART will achieve viral suppression. While the number...
