Category Archives: Delivery arrangements
How care is organized
Global coverage of interventions for reduction of injecting drug use-related harm, HIV, viral hepatitis and tuberculosis in prisons and other carceral settings: A systematic review
BACKGROUND: People who are incarcerated experience disproportionately high rates of injecting drug use and infectious disease, including HIV, viral hepatitis and tuberculosis. However, comprehensive global data regarding the availability of...
A systematic review and meta-analysis on the association between antiretroviral therapy refill type and viral suppression
To reduce barriers to viral suppression, people living with HIV (PLWH) are placed on multi-month dispensing (MMD)of antiretroviral therapy medication. However, there are concerns about viral rebound following MMD initiation,...
Rapid diagnostic tests, laboratory-based immunoassay and nucleic acid testing strategies for long-acting injectable pre-exposure prophylaxis: A systematic review and meta-analysis
Background Long-acting injectable pre-exposure prophylaxis (LAI-PrEP) is a highly effective biomedical intervention for the prevention of HIV acquisition. There is a strong interest among communities and policymakers for LAI-PrEP scale-up,...
Effectiveness of mobile health (mHealth) interventions on ART adherence among people living with HIV in low- and middle-income countries: A systematic review and meta-analysis
Antiretroviral therapy (ART) is essential for HIV treatment, yet maintaining high adherence remains challenging in resource-limited settings. Mobile health (mHealth) interventions offer a scalable approach to support adherence. This meta-analysis...
Worldwide changes in HIV-related stigma among people living with HIV: A cross-temporal meta-analysis and systematic review
Background: HIV-related stigma among people living with HIV has emerged as a growing public health concern, yet limited longitudinal data are available to characterize its evolution over time. In this study,...
Barriers and facilitators influencing PrEP uptake among men who have sex with men and transgender women in the United States: A systematic review
In the United States, men who have sex with men (MSM) and transgender women (TGW) have high HIV pre-exposure prophylaxis (PrEP) awareness, yet uptake rates remain extremely low. This signifies...
Commonality and co-occurrence of discrete strategies within implementation strategy bundles: Findings from the Living Database of HIV Implementation Science systematic review, 2014-2021
Background HIV services and innovations are delivered through implementation strategy bundles that are often complex, comprising numerous discrete strategies. Systematically characterizing the use patterns of discrete strategies may inform strategy...
PrEP delivery for U.S. adolescents and young adults: A systematic review and narrative synthesis
Despite proven efficacy in preventing human immunodeficiency virus (HIV) transmission, pre-exposure prophylaxis (PrEP) remains underutilized among adolescents and young adults (AYA) in the United States (US). This systematic review and...
Interventions to improve HIV care and treatment outcomes among people with HIV who have substance use disorder or at-risk substance use: A narrative review
Substance use adversely affects engagement in HIV care, adherence to medication, and HIV viral suppression. This review assessed the scope of US interventions designed to promote positive outcomes along the...
Inconsistent condom use and its associated factors among female sex workers in African countries: Systematic review and meta-analysis
Background Inconsistent condom use represents the most proximal behavioral risk factor for acquisition and transmission of sexually transmitted infections, including human immunodeficiency virus. However, certain situations hinder female sex workers...
Knowledge of reproductive-age women about mother-to-child transmission of HIV and associated factors: A systematic review and meta-analysis
INTRODUCTION: Despite significant efforts to manage and prevent HIV, knowledge gaps persist regarding mother-to-child transmission of HIV among women of reproductive age. Previous studies, limited in scope and producing inconsistent...
Peer network approaches for improving HIV testing, prevention and care utilisation among men in sub-Saharan Africa: A scoping review
INTRODUCTION: Limited male engagement in HIV prevention and care is a global challenge more pronounced in sub-Saharan Africa (SSA) contributing to ongoing transmission. However, peer network interventions show promise in...
