Category Archives: Governance arrangements
How decisions about care are made
Maternal HIV infection and antiretroviral therapy in pregnancy: Implications for vertical transmission, fetal safety, and long-term infant outcomes
HIV mother-to-child transmission (MTCT) continues to pose a significant public health challenge, especially in regions with limited resources, although the worldwide distribution of antiretroviral therapy (ART) has drastically lowered the...
Oral pre-exposure prophylaxis retention among men who have sex with men and transgender persons: Systematic review and meta-analysis
Successful implementation of oral pre-exposure prophylaxis (PrEP) requires retention in PrEP care among those with an increased likelihood of HIV. This study aimed to estimate the proportion of retention on...
Seroprevalence of transfusion-transmitted infections among blood donors in India: A systematic review and meta-analysis
BACKGROUND AND OBJECTIVES: Blood transfusion is essential in healthcare but carries inherent risks of human immunodeficiency virusAÿ(HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and malaria transmission. National...
Immunogenicity and safety of the booster COVID-19 vaccine among people with HIV: A systematic review and meta-analysis
Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...
Prevalence and factors influencing HIV testing behavior in adolescents and young adults: A systematic review and meta-analysis
Objective To systematically evaluate the prevalence and influencing factors of human immunodeficiency virus (HIV) testing among adolescents and young adults (10–25 years old), providing a reference for optimizing testing strategies and...
Artificial intelligence for HIV care: A global systematic review of current studies and emerging trends
INTRODUCTION: Artificial intelligence (AI) and, in particular, machine learning (ML) have emerged as transformative tools in HIV care, driving advancements in diagnostics, treatment monitoring and patient management. The present review...
Hepatitis C increases acute myocardial infarction risk in people living with HIV: A systematic review and meta-analysis
BackgroundHepatitis C virus (HCV) coinfection is common among people living with HIV (PLWH) and is associated with adverse outcomes. However, the specific association between HCV coinfection and the risk of...
Advanced stage disease progression and mortality rate before and after the implementation of the Universal Test and Treat strategy (UTT) for HIV patients in Ethiopia: A systematic review and meta-analysis
BACKGROUND: The universal test and treat (UTT) program, is a strategy for eliminating HIV and, it involves screening all populations at risk for HIV infection, initiating early treatment for those...
Prevalence of opportunistic bacterial infections (tuberculosis and pneumonia) among people with HIV in Ethiopia: Systematic review and meta-analysis
BACKGROUND: Individuals with weakened immune systems, such as those living with Human Immunodeficiency Virus (HIV), are more vulnerable to opportunistic bacterial infections, which include tuberculosis and pneumonia. This systematic review...
HIV-related mortality time trends among children and young adolescents on antiretroviral therapy by age, treatment duration, and region: A systematic review and meta-regression analysis
Background: Past cohort studies have examined mortality among children and young adolescents (aged 0–14 years) who have received antiretroviral therapy (ART), but no systematic reviews have been undertaken to synthesise these...
Cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (2019-2025): A systematic review
INTRODUCTION: This systematic review synthesizes recent evidence on the cost-effectiveness of HIV prevention interventions in sub-Saharan Africa (SSA), where over 70% of the global HIV burden resides. METHODS: Following PRISMA...
Probability of vertical HIV transmission: A systematic review and meta-regression
Background Eliminating HIV vertical transmission is a global priority and monitored by estimating paediatric HIV infections with the UNAIDS-supported Spectrum AIDS Impact Module (Spectrum-AIM). Recent innovations in antiretroviral therapy (ART)...
