HIV Pre-exposure prophylaxis in the LGBTQ Community: A review of practice and places


One in six bisexual and gay men will be diagnosed with HIV in their lifetime (Human Rights Campaign, 2017). Without a vaccine or cure, prevention may be the best tool to control the HIV pandemic. Since 2012, the World Health Organization (WHO) recommends HIV pre-exposure prophylaxis (PrEP) for a high-risk population. To this day, in the United States (U.S.), the group with the highest risk is MSM (men who have sex with other men) that have condom-less sexual intercourse (Center for Disease Control and Prevention, 2019). In fact, in 2018, over 50% of all HIV infections occurred in MSM and members of the LGBT community. A systematic review was conducted using PubMed, Google Scholar, and Cochrane Library. The inclusive criteria were articles published from 2015–2020, focusing specifically on HIV PrEP among the members of the LGBTQ+ community. The keywords for our search were “Pre-exposure prophylaxis,” “HIV,” “men who have sex with other men” (MSM), “Bisexual,” “transgender.” A total of 25 articles met the inclusion criteria. About 50% of the articles focused on MSM while others highlighted bisexual and transgender women. Globally, PrEP is a priority. Programs to educate and promote its use are being developed, but challenges are present regarding access to PrEP and its maintenance for longer than 12 months. In the U.S., PrEP programs started in 2012, intending to promote and educate. Research shows that more than 60% of the high-risk patients are willing to try PrEP if they are correctly educated, showing that physicians were not doing a thorough job educating their patients. PrEP is essential for preventing the transmission of HIV among the LGBTQ+ subpopulation. Existing gaps need to be bridged to create or improve to educate high-risk populations and physicians on HIV PrEP.


Dorce-Medard DOJ, Okobi Md OE, Grieb DO J, Saunders DO N, Harberger S




  • Population(s)
    • Men who have sex with men
    • Transgender communities
  • Prevention, Engagement and Care Cascade
    • Prevention
  • Prevention
    • Biomedical interventions


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