Impact of nonadherence to antiretroviral therapy (ART) on population-level health outcomes
Abstract
- Several studies analyze overall healthcare costs, pharmacy costs, and cost savings among people living with HIV relative to level of ART adherence.
- Generally, adherence to ART appears to predict levels of healthcare utilization, with studies reporting that poorer adherence to ART results in increased utilization, and better adherence results in decreased utilization.
- Suboptimal adherence to ART appears to contribute to a higher risk of mortality.
- Poor adherence to ART in pediatric HIV care may continue into adulthood and in some cases, can contribute to mortality.
- Acquired HIV drug resistance can occur when an individual living with HIV has poor adherence to ART, though this can vary, depending on the class of antiretrovirals in the prescribed regimen.
Authors
Ontario HIV Treatment Network: Rapid Response Service
Year
2021
Topics
- Population(s)
- Men who have sex with men
- General HIV+ population
- Prevention, Engagement and Care Cascade
- Engagement and Care Cascade
- Engagement and Care Cascade
- Treatment
