Interventions for tobacco use cessation in people living with HIV and AIDS: Cochrane nursing care field – Cochrane review summary


Interventions for tobacco use cessation in people living with HIV and AIDS. Cochrane Database of Systematic Reviews, 6, Article Number CD011120.
For people living with HIV (PLWH), antiretroviral therapy has had a major impact on morbidity and mortality rates. Specifically, PLWH are now living longer; life expectancy is now comparable to the general population; and cause of death is more likely to be attributed to a chronic, non-HIV-related illness such as heart disease or lung cancer. In fact, lung cancer is the most prevalent, non-HIV-related cancer amongst PLWH (Molt o, Moran, Sirera, & Clotet, 2015). Research has indicated that, when compared with the general population, tobacco consumption and smoking-related disease is significantly greater in this group. A contributing factor is that sustained tobacco use is frequently adopted as a coping mechanism to combat HIV-related symptoms such as neuropathy, depression, and anxiety. Additionally, there is evidence to suggest that PLWH have higher nicotine dependency levels that have a negative impact on the severity of withdrawal symptoms and an individual’s ability to achieve long-term success following tobacco use cessation. Furthermore, tobacco use in PLWH results in higher levels of immune exhaustion and impaired T cell functioning when compared to nonsmoking PLWH.


Stott A




  • Population(s)
    • General HIV+ population
  • Substance Use
    • Tobacco


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