SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV pre-exposure prophylaxis and its impact on the gut microbiome in men having sex with men

2022

HIV/AIDS still imposes a high epidemiological and societal burden. Together with antiretroviral therapy, pre-exposure prophylaxis (PrEP) represents a fundamental tool in the fight against HIV/AIDS. PrEP is considered effective and...

Peer education and peer counselling for health and well-being: A review of reviews

2022

Peer education and peer counselling for health and wellbeing have been recognized as complementary approaches to professional intervention for over 50 years, but it is relatively recently that research into...

CRISPR-edited stem cell transplantation for HIV-related gene modificationin vivo: A systematic review

2022

BACKGROUND: CRISPR is a novel genomic editing technology which can be useful for the treatment of immune diseases such as HIV. However, the application of CRISPR in stem cells for...

Strategies to improve HIV care outcomes for people with HIV who are out of care

2022

Objective: The aim of this study was to evaluate the effectiveness of five intervention strategies: patient navigation, appointment help/alerts, psychosocial support, transportation/appointment accompaniment, and data-to-care on HIV care outcomes among persons...

Effects of physical activity interventions on health outcomes among older adults living with HIV: A systematic review and meta-analysis

2022

There is a lack of evidence regarding the effects of exercise on older individuals living with HIV. This systematic review and meta-analysis examined previous studies on physical activity interventions for...

Blood-borne virus testing in emergency departments—A systematic review of seroprevalence, feasibility, acceptability and linkage to care

2022

BACKGROUND: Blood-borne viruses (BBVs) cause significant morbidity and mortality worldwide. Emergency departments (EDs) offer a point of contact for groups at increased risk of BBVs who may be less likely...

Trends and clinical characteristics of HIV and caerebrovascular disease in low- and middle-income countries (LMICs) Between 1990 and 2021

2022

PURPOSE OF THE REVIEW: To describe trends and clinical characteristics of HIV and cerebrovascular disease between 1990 and 2021 in LMICs and identify the gaps in our understanding. RECENT FINDINGS:...

Economic benefits of the United States’ AIDS drug assistance program: A systematic review of cost analyses to guide research and policy priorities

2022

As part of the Ryan White HIV/AIDs Program, the federally-funded, state-administered AIDS Drug Assistance Program (ADAP) provides prescription drug medications, including antiretroviral therapy, for people with HIV (PWH) who are...

HIV voluntary counseling and testing (VCT-HIV) effectiveness for sexual risk-reduction among key populations: A systematic review and meta-analysis

2022

Background: HIV disproportionately affects people who inject drugs, transgender people, sex workers, men who have sex with men, and incarcerated people. Recognized as key populations (KP), these groups face increased impact...

Markers of ovarian reserve in women living with HIV: A systematic review

2022

Background: Anti-Mullerian hormone (AMH) levels indicate ovarian reserve and are predictive of reproductive aging. Studies evaluating AMH levels in women with HIV have produced conflicting results, and reasons for inter-study differences...

Health determinants in men of the Bear subculture compared with the MSM population. Literature review

2022

A number of health problems are more common in the population of men who have sex with men (MSM) as compared with the general population. At the same time, research...

Pulmonary arterial hypertension in patients infected with the human immunodeficiency virus

2022

It is important to recognize and treat human immunodeficiency virus-associated pulmonary arterial hypertension (HIV-PAH) because of the associated morbidity and mortality. With the introduction of antiretroviral therapies (ART), improved survival...

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