SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Risk factors for types of recurrent tuberculosis (reactivation versus reinfection): A global systematic review and meta-analysis

2022

Background The purpose of this meta-analysis (PROSPERO number: CRD42021243204) is to perform extensive and penetrating analyses on the risk factors associated with reactivation or reinfection. Methods We searched PubMed and...

Vitamin D and calcium supplementation reverses tenofovir-caused bone mineral density loss in people taking ART or PrEP: A systematic review and meta-analysis

2022

BACKGROUND: The decrease of bone mineral density (BMD) after the intake of Tenofovir disoproxil fumarate (TDF)-based drugs in people living with HIV/AIDS (PLWHA) and HIV-negative key populations under pre-exposure prophylaxis...

Use of HIV recency assays for HIV incidence estimation and other surveillance use cases: Systematic review

2022

BACKGROUND: HIV assays designed to detect recent infection, also known as “recency assays,” are often used to estimate HIV incidence in a specific country, region, or subpopulation, alone or as...

eHealth interventions to address HIV and other sexually transmitted infections, sexual risk behavior, substance use, and mental ill-health in men who have sex with men: Systematic review and meta-analysis

2022

Background: Men who have sex with men experience disproportionately high levels of HIV and other sexually transmitted infections (STIs), sexual risk behavior, substance use, and mental ill-health. These experiences are interrelated,...

Prevalence of occult hepatitis B among HIV-positive individuals in Africa: A systematic review and meta-analysis

2022

The prevalence of hepatitis B virus among HIV-seropositive individuals is believed to be high, and yet the disease remains neglected in many areas of the continent. Little is known about...

Evidence and implication of interventions across various socioecological levels to address HIV testing uptake among men who have sex with men in the United States: A systematic review

2022

OBJECTIVES: Strengthening HIV testing uptake is critical to curtail the HIV epidemics among men who have sex with men in the United States. Despite the implementation of various interventions to...

Frameworks and measures for HIV-related internalized stigma, stigma and discrimination in healthcare and in laws and policies: A systematic review

2022

INTRODUCTION: There is strong global commitment to eliminate HIV-related stigma, and work in this area continues to evolve. Wide variation exists in frameworks and measures used. METHODS: Building on the...

Comparison of the efficacy and safety of a doravirine-based, three-drug regimen in treatment-naive HIV-1 positive adults: A bayesian network meta-analysis

2022

Introduction: Extensive use of antiretroviral therapy has remarkably improved the survival rates of people living with HIV. Doravirine (DOR) is a newly-approved antiretroviral belonging to the class of non-nucleoside reverse...

Impact of antiretroviral therapy on oral health among children living with HIV: A systematic review and meta-analysis

2022

Oral health is an integral component of general health and well-being but might be undermined among children living with HIV (CLWH) due to the condition itself or the antiretroviral therapy...

The global burden of cognitive impairment in people living with HIV: A systematic review and meta-analysis

2022

Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for...

Psychosocial interventions for depression delivered by non-mental health specialists to people living with HIV/AIDS in low- and middle-income countries: A systematic review

2022

Background: Depression commonly co-exists with human immunodeficiency virus (HIV), but in low- and middle-income countries (LMICs), where the HIV burden is greatest, mental health resources are limited. These settings may benefit...

A systematic review and meta-analysis to estimate the time from HIV infection to diagnosis for people with HIV

2022

Timely HIV diagnosis is critical to minimizing transmission events. We sought to estimate the meantime from HIV infection to diagnosis and its temporal trend among people with HIV. Following Preferred...

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