SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Overcoming structural barriers to diffusion of HIV pre-exposure prophylaxis

2023

HIV prevention with antiretroviral medication in the form of pre-exposure prophylaxis (PrEP) offers a critical tool to halt the HIV pandemic. Barriers to PrEP access across drug types, formulations, and...

Anti-cytomegalovirus preemptive therapy to prevent cytomegalovirus disease in HIV-infected patients: A systematic review

2023

BACKGROUND: HIV patients are at higher risk of contracting and developing into an asymptomatic form of CMV infection. This review aimed to evaluate the efficacy and safety of preemptive therapy...

Health economic analyses of latent tuberculosis infection screening and preventive treatment among people living with HIV in lower tuberculosis incidence settings: A systematic review

2023

Introduction: In lower tuberculosis (TB) incidence countries (<100 cases/100,000/year), screening and preventive treatment (PT) for latent TB infection (LTBI) among people living with HIV (PLWH) is often recommended, yet guidelines...

Immediate treatment for recent hepatitis C infection in people with high-risk behaviors: A systematic review and meta-analysis

2023

BACKGROUND AND AIMS: Direct-acting antivirals (DAAs) are almost exclusively approved for the treatment of chronic HCV. This poses a significant barrier to the treatment of recently acquired HCV because of...

A scoping review of lung function in children and adolescents living with HIV in the era of antiretroviral treatment

2023

Background: Human immunodeficiency virus (HIV) in children and adolescents remains an important health challenge in many countries and is commonly associated with lung disease. The introduction of antiretroviral therapy (ART) has...

The risk of sexual transmission of HIV in individuals with low-level HIV viraemia: A systematic review

2023

BACKGROUND: The risk of sexual transmission of HIV from individuals with low-level HIV viraemia receiving antiretroviral therapy (ART) has important public health implications, especially in resource-limited settings that use alternatives...

Barriers to pre-exposure prophylaxis (PrEP) use for HIV: An integrative review

2023

OBJECTIVES: to identify and synthesize scientific evidence on the barriers and difficulties for Pre-exposure Prophylaxis (PrEP) use and compliance for HIV. METHODS: an integrative literature review, using the MEDLINE/PubMed, Cumulative...

New treatment strategies for HIV-positive cancer patients undergoing anticancer medical treatment: Update of the literature

2023

The introduction of highly active antiretroviral therapy (ART) has deeply modified the outcome of HIV patients by improving their overall survival and ameliorating their quality of life (QoL). The prolongation...

A review of bidimensional acculturation and STI/HIV-related sexual risk behaviours among Hispanic youth

2023

A growing body of research suggests that acculturation may play a role in the disproportionate likelihood of sexual risk behaviour and STI/HIV infection among Hispanic youth in the USA. We...

Prevalence and predictors of virological failure in pediatric patients on HAART in sub-Saharan Africa: A systematic review and meta-analysis

2023

Antiretroviral treatment failure has emerged as a challenge in the management of pediatric human immunodeficiency virus (HIV) patients, especially in resource-limited countries despite accessibility to Highly Active Antiretroviral Therapy (HAART)....

Evaluation of HIV screening in hospital emergency services. Systematic review

2023

AIM: To evaluate HIV screening of people attending emergency services. DESIGN: Systematic review. DATA SOURCES: CINAHL Complete, Cochrane Library, Cuiden Plus, PubMed, PsycINFO, SCOPUS and Web of Science. REVIEW METHODS:...

Prevalence of HIV, hepatitis B virus, hepatitis C virus, drug use, and sexual behaviors among street children in Iran: A systematic review and meta-analysis

2023

Background and Aims Street children face a disproportionately higher risk of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) due to high‐risk sexual and drug use...

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