SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Impact of antiretroviral therapy on kidney disease in HIV infected individuals—A qualitative systematic review

2022

Kidney disease is the fourth most common cause of non-AIDS-related mortality in people living with HIV. Combination antiretroviral therapy (cART) remains the cornerstone of treatment. However, little is known about...

National burden of intestinal parasitic infections and its determinants among people living with HIV/AIDS on anti-retroviral therapy in Ethiopia: A systematic review and meta-analysis

2022

Objectives: The aim of this systematic review and meta-analysis is designed to assess the pooled prevalence and determine risk factors of intestinal parasitic infections among people living with HIV/AIDS on anti-retroviral...

Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: A systematic review and meta-analysis

2022

Background: There are 15·4 million children who are HIV-exposed and uninfected worldwide. Early child development crucially influences later academic and socioeconomic factors. However, the neurodevelopmental outcomes of HIV-exposed uninfected (HEU) children...

Risk of mortality in HIV-infected COVID-19 patients: A systematic review and meta-analysis

2022

Background The relationship between HIV infection and COVID-19 clinical outcomes remains a significant public health research problem. We aimed to determine the association of HIV comorbidity with COVID-19 mortality. Methods...

Global burden of Cyclospora cayetanensis infection and associated risk factors in people living with HIV and/or AIDS

2022

Cyclospora cayetanensis infections remain one of the most common protozoan opportunistic causes of gastrointestinal diseases and diarrhea among people living with HIV and/or AIDS (PLWHA). This study was conducted to provide...

HIV testing uptake according to opt-In, opt-out or risk-based testing approaches: A systematic review and meta-analysis

2022

Purpose of review: Improving HIV testing uptake is essential to ending the HIV pandemic. HIV testing approaches can be opt-in, opt-out or risk-based. This systematic review examines and compares the uptake...

Same-day and rapid initiation of antiretroviral therapy in people living with HIV in Asia. How far have we come?

2022

Human immunodeficiency virus (HIV) continues to be a major public health issue, and the effectiveness of HIV prevention, diagnosis, treatment, and care varies, particularly in the Asia-Pacific region. The rapid...

Storyboarding HIV infected young people’s adherence to antiretroviral therapy in lower- to upper middle-income countries: A new-materialist qualitative evidence synthesis

2022

Young people living with perinatal infections of Human Immunodeficiency Virus (YLPHIV) face a chronic disease, with treatment including adherence to lifelong antiretroviral treatment (ART). The aim of this QES was...

Determinants of voluntary counseling and testing service uptake among adult sub-Saharan Africans: A systematic review and meta-analysis

2022

Objective: To examine the major determinants of VCT service uptake among adults in SSA. Methods: Electronic databases were searched to identify eligible English language publications. Reporting of the study selection...

Integrating HIV and mental health interventions to address a global syndemic among men who have sex with men

2022

In this Series paper, we review evidence on the co-occurring and synergistic epidemics (syndemic) of HIV and mental health problems worldwide among men who have sex with men (MSM). The...

Adolescent girls and young women’s experiences of living with HIV in the context of patriarchal culture in sub-Saharan Africa: A scoping review

2022

Adolescent girls and young women (AGYW) in sub-Saharan Africa are disproportionately affected by the human immunodeficiency virus (HIV) due to socio-cultural gender, power, and economic disparities. This scoping review examined...

APOBEC3, TRIM5α, and BST2 polymorphisms in healthy individuals of various populations with special references to its impact on HIV transmission

2022

AIDS restriction genes (ARGs) like APOBEC3, TRIM5α, and BST2 can act as immunological detectors of the innate protective mechanism of the body. ARGs influence the course of viral pathogenesis and...

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