SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Health-related quality of life in patients with different diseases measured with the EQ-5D-5L: A systematic review

2021

Background: The EQ-5D-5L is a generic preference-based questionnaire developed by the EuroQol Group to measure health-related quality of life (HRQoL) in 2005. Since its development, it has been increasingly applied...

A critical review of symptom management nursing science on HIV-related fatigue and sleep disturbance

2021

Despite improved antiretroviral treatments, people living with HIV (PLWH) continue to suffer from HIV-related fatigue and sleep disturbances. We first reviewed the definition, etiology, and research breakthroughs of HIV-related fatigue...

Academic detailing to increase prescribing of HIV pre-exposure prophylaxis

2021

Although HIV pre-exposure prophylaxis can decrease new cases of HIV by up to 99%, many patients who could benefit from pre-exposure prophylaxis never receive prescriptions for it. Because pre-exposure prophylaxis...

Declining HIV incidence in sub-Saharan Africa: A systematic review and meta-analysis of empiric data

2021

Introduction: UNAIDS models suggest HIV incidence is declining in sub-Saharan Africa. The objective of this study was to assess whether modelled trends are supported by empirical evidence. Methods: We conducted a systematic...

Experience of chronic noncommunicable disease in people living with HIV: A systematic review and meta-aggregation of qualitative studies

2021

BACKGROUND: An increasing number of people living with HIV (PLWH) have had chronic noncommunicable diseases (NCDs) over the last 5 years. However, robust evidence regarding the perception and challenges of...

Dual contraceptive use and factor associated with people living with HIV/AIDS: A systematic review and meta-analysis

2021

INTRODUCTION: A dual contraceptive method is the usage of any modern contraceptive method with male or female condoms which could lower sexually transmitted diseases and unwanted pregnancy. Ethiopian standard utilization...

A review of chronic comorbidities in adults living with HIV: State of the science

2021

People living with HIV are living longer, high-quality lives; however, as they age, this population is at increased risk for developing chronic comorbidities, including cardiovascular disease, certain types of cancer...

Psychosocial needs and vulnerabilities of older gay and bisexual men

2021

Key take-home messages Health outcomes related to the intersectionality of aging and sexual minority status is an emerging area of research. It is important to consider the context of lived...

ABO blood groups and risk of human immunodeficiency virus infection: A systematic review and meta-analysis

2021

The last few decades have seen a pandemic of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), which continues to cause substantial morbidity and mortality. ABO blood groups are anthropological and...

Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: A narrative overview

2021

BACKGROUND: South Africa, with one of the highest HIV prevalences in the world, introduced the universal test and treat (UTT) programme in September 2016. Barriers to sustained viral suppression may...

Mental health symptoms associated with sexualized drug use (chemsex) among men who have sex with men: A systematic review

2021

BACKGROUND: Sexualized drug use (SDU), also known as chemsex, refers to the use of psychoactive substances for sexual purposes among men who have sex with men (MSM), which has been...

Isoniazid preventive therapy plus antiretroviral therapy for the prevention of tuberculosis: A systematic review and meta-analysis of individual participant data

2021

Background: Isoniazid preventive therapy prevents active tuberculosis in people with HIV, but previous studies have found no evidence of benefit in people with HIV who had a negative tuberculin skin...

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