SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Low inducibility of latent human immunodeficiency virus type 1 proviruses as a major barrier to cure

2021

The latent reservoir for human immunodeficiency virus type 1 (HIV-1) in resting CD4+ T cells is a major barrier to cure. The dimensions of the reservoir problem can be defined...

Worldwide relative smoking prevalence among people living with and without HIV: a systematic review and meta-analysis

2021

OBJECTIVE AND DESIGN: People living with HIV (PLH) suffer disproportionately from the chronic diseases exacerbated by smoking tobacco. We performed a systematic review and meta-analysis to establish the relative prevalence...

Public-private partnerships in primary health care: A scoping review

2021

BACKGROUND: The Astana Declaration on Primary Health Care reiterated that PHC is a cornerstone of a sustainable health system for universal health coverage (UHC) and health-related Sustainable Development Goals. It...

Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living With human immunodeficiency virus: Systematic review and meta-analysis of diagnostic test accuracy studies

2021

Cryptococcal antigen (CrAg) detection could direct the timely initiation of antifungal therapy. We searched MEDLINE and Embase for studies where CrAg detection in serum/cerebrospinal fluid (CSF) and CSF fungal culture...

HIV among men who have sex with men in the Caribbean: Reaching the left behind

2021

OBJECTIVES: To present the epidemiology, social and cultural factors driving the HIV epidemic among men who have sex with men (MSM) in the Caribbean region and to highlight the regional...

Missed opportunities for sexually transmitted infections testing for HIV pre-exposure prophylaxis users: A systematic review

2021

Introduction: Given the synergistic relationship between HIV and sexually transmitted infections (STI), the integration of services has the potential to reduce the incidence of both HIV and STIs. We explored the...

Effects of HAART in the nutritional status of children and adolescents infected by HIV in Brazil: A systematic review

2021

The verification of factors associated with growth, body composition and nutritional and nutritional aspects after HIV infection in children or adolescents in Brazil is fundamental for progress in this area....

Motherhood and decision-making among women living with HIV in developed countries: A systematic review with qualitative research synthesis

2021

BACKGROUND: Women living with HIV (WLH) lack evidence-based information about reproductive options while managing pressures from family, clinicians, and communities to give up the idea of having children. As the...

Economic evaluation of HIV testing options for low-prevalence high-income countries: A systematic review

2021

INTRODUCTION: This study reviewed the economic evidence of rapid HIV testing versus conventional HIV testing in low-prevalence high-income countries; evaluated the methodological quality of existing economic evaluations of HIV testing...

Current evidence on the adoption of indicator condition guided testing for HIV in western countries: A systematic review and meta-analysis

2021

BACKGROUND: Indicator condition (IC) guided testing for HIV is an effective way to identify undiagnosed people living with HIV, but studies suggest its implementation is lacking. This systematic review provides...

Global systematic review of common mental health disorders in adults living with HIV

2021

PURPOSE OF THE REVIEW: By reviewing the most recent common mental health disorders (CMHD) studies in people living with HIV (PLWH) (2018-2020), this review discusses the prevalence of CMHD, factors...

The likelihood of severe COVID-19 outcomes among PLHIV with various comorbidities: A comparative frequentist and Bayesian meta-analysis approach

2021

INTRODUCTION: The SARS-CoV-2 virus can currently pose a serious health threat and can lead to severe COVID-19 outcomes, especially for populations suffering from comorbidities. Currently, the data available on the...

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