SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

Background Human immunodeficiency virus (HIV) and COVID-19 continue to pose significant global public health challenges. Although vaccination is essential for preventing COVID-19 in people with HIV (PWH), evidence on the...

OBJECTIVE: To review the efficacy and safety of lenacapavir for the prevention of HIV-1 infection. DATA SOURCES: Clinical trials and review articles were obtained through August 2025 using search terms...

Integrase strand transfer inhibitors (INSTIs) have emerged as cornerstone agents in global antiretroviral therapy, though growing drug resistance presents clinical challenges. Conventional Sanger sequencing may underestimate the burden of low-frequency...

OBJECTIVES: Tuberculosis and Human Immunodeficiency Virus (HIV) are two diseases that have imposed the heaviest burden globally. This study aims to determine the global prevalence of Mycobacterium tuberculosis and HIV...

Objective: To examine the prevalence of current substance and hazardous alcohol use in people with HIV and tuberculosis (TB) disease and its impact on TB treatment outcomes. Methods: A systematic review following...

BACKGROUND: Pregnant women living with HIV are known to be at higher risk of depression than pregnant women without HIV. Accompanied by a systematic literature review, the aim of this...

Human immunodeficiency virus (HIV) remains a public health issue in the U.S., affecting approximately 1.2 million individuals, many of whom are unaware of their infection status. This study reviews predictors...

BACKGROUND: Cyclospora cayetanensis is a coccidian protozoan parasite belonging to the phylum Apicomplexa. This systematic review and meta-analysis aimed to assess the prevalence and risk factors of C. cayetanensis in...

Transgender individuals, whose gender identity differs from their assigned sex at birth, often undergo pharmacotherapy, including hormone therapy (HT), as part of their gender-affirming care. This pharmacotherapy, particularly when combined...

INTRODUCTION: Black/African American men who have sex with other men (BMSM) are disproportionately affected by HIV, experience significant disparities in HIV incidence, and face significant barriers to accessing HIV treatment...

Background: Adolescents and young adults (AYA) make up a significant share of the world’s burden of HIV and other sexually transmitted infections (STI). Self-testing can increase testing coverage and strengthen the...

Objectives: The objective of this review was to assess the effectiveness of HIVST in terms of increasing HIV testing, early detection of HIV, and sexually transmitted infections among MSM via...