SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Late diagnosis of human immunodeficiency virus (HIV) and its associated factors in Asian countries: A systematic review

2025

Background: Despite widespread public health interventions and research on Human Immunodeficiency Virus (HIV), late diagnosis and presentation into care constitute serious challenges to effective prevention and control of the disease. Asia,...

A systematic review of prolonged SARS-CoV-2 shedding in immunocompromised persons

2025

Background Although reports have documented prolonged SARS‐CoV‐2 RNA detection in immunocompromised patients, few studies have systematically analyzed data on duration of SARS‐CoV‐2 in respiratory specimens of immunocompromised patients. Methods A...

Seroprevalence of transfusion-transmitted infections among blood donors in India: A systematic review and meta-analysis

2025

BACKGROUND AND OBJECTIVES: Blood transfusion is essential in healthcare but carries inherent risks of human immunodeficiency virusAÿ(HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), syphilis and malaria transmission. National...

Access and utilization of HIV/STI testing services among men who have sex with men during the COVID-19 pandemic: A systematic review

2025

Background: Men who have sex with men (MSM) continue to bear the disproportionate burden of HIV and other sexually transmitted infections (STIs). The public health response to the COVID-19 pandemic...

Reducing HIV risk behaviors among Black women living with and without HIV/AIDS in the U.S.: A systematic review

2025

This systematic review provides an examination of the status of HIV/AIDS prevention interventions for Black, heterosexual women in the U.S. from 2012 to 2019. Using PRISMA guidelines, 28 interventions were...

The pathological link between elevated markers of inflammation, endothelial activation, and cardiovascular diseases in people living with HIV on combination antiretroviral therapy: A systematic review

2025

Introduction Despite administering combination antiretroviral therapy (cART), people living with the human immunodeficiency virus (PLWH) have been identified to be at an elevated risk of cardiovascular diseases (CVDs). Notably, inflammation...

Pharmacogenetics in tuberculosis-HIV coinfected populations: A systematic review of genetic variants influencing antiretroviral and anti-tuberculosis drug response

2025

Pharmacogenetics is a concept designed to tailor medication based on genetic profile to improve efficacy and reduce adverse effects. This personalized strategy shows considerable potential for populations facing complicated therapeutic...

Safety and efficacy of long-acting cabotegravir/rilpivirine versus standard oral antiretroviral therapy: A systematic review and meta-analysis

2025

Background In 2023, there were 39.9 million people living with HIV (PLWH) worldwide and 630 000 deaths related to HIV. New strategies are needed, and long-acting antiretrovirals (LAAs) are now widely...

Global epidemiology of HIV among dialysis patients: A systematic review and meta-analysis

2025

HIV transmission and infection among dialysis patients have become a major healthcare concern and a rising threat throughout the world. Our current systematic review and meta-analysis targeted to determine the...

Incidence of adverse drug reactions among HIV patients on antiretroviral drugs in Ethiopia: A systematic review and meta-analysis

2025

Introduction: In recent decades, AIDS–related illnesses have declined due to the widespread use of highly active antiretroviral therapy (HAART). Despite the numerous benefits that HAART provides, it causes significant challenges for...

PrEP uptake and utilisation among adolescent girls and young women in Sub-Saharan Africa: A scoping review

2025

Adolescent girls and young women (AGYW) in sub-Saharan Africa (SSA) are disproportionately affected by HIV. Despite the effectiveness of oral pre-exposure prophylaxis (PrEP) in preventing HIV, uptake and effective utilisation...

Undetectable = Untransmittable: A cross-population systematic review and meta-analysis on awareness and acceptance

2025

The Undetectable = Untransmittable (U=U) message is a cornerstone of HIV-related public health communication, yet global levels of awareness and acceptance remain unclear across key populations. This study aimed to...

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