SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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The likelihood of severe COVID-19 outcomes among PLHIV with various comorbidities: A comparative frequentist and Bayesian meta-analysis approach

2021

INTRODUCTION: The SARS-CoV-2 virus can currently pose a serious health threat and can lead to severe COVID-19 outcomes, especially for populations suffering from comorbidities. Currently, the data available on the...

Incentive-based human immunodeficiency virus Screening in low and middle income countries: A systematic review

2021

BACKGROUND: The majority of new HIV infections that occur worldwide are in sub-Saharan Africa. While recent gains have been made in many low and middle income countries (LMIC), substantial disparities...

Magnetic resonance imaging as a biomarker in diabetic and HIV-associated peripheral neuropathy: A systematic review-based narrative

2021

Background: Peripheral neuropathy can be caused by diabetes mellitus and HIV infection, and often leaves patients with treatment-resistant neuropathic pain. To better treat this condition, we need greater understanding of...

Effectiveness of eHealth interventions for HIV prevention and management in sub-Saharan Africa: Systematic review and meta-analyses

2021

HIV is still the leading cause of death in Sub-Saharan Africa (SSA), despite medical advances. eHealth interventions are effective for HIV prevention and management, but it is unclear whether this...

A review of the state of HIV nursing science with sexual orientation, gender identity/expression peoples

2021

Throughout the HIV pandemic, nurses have contributed to or led approaches to understanding the effects of HIV disease at individual and societal levels. Nurses have advocated for socially just care...

Impact of chronic HIV infection on SARS-CoV-2 infection, COVID-19 disease and vaccines

2021

PURPOSE OF REVIEW: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into a global pandemic that affect the health of hundreds of millions worldwide. In particular, SARS-CoV-2 infection...

The effects of antidepressant medications on antiretroviral treatment adherence in HIV-positive individuals with depression

2021

Background Extant literature has identified Major Depressive Disorder (MDD) as a comorbid disorder in individuals with seropositive human immunodeficiency disorder (HIV), and this may affect HIV-treatment efficacy. However, there is...

Challenges to the conceptualization and measurement of resilience in HIV research

2021

The purpose of this study was to evaluate the conceptualization and measurement of resilience in HIV research. Terms related to resilience and HIV were searched in three databases to identify...

HIV/AIDS late presentation and its associated factors in China from 2010 to 2020: A systematic review and meta-analysis

2021

Background Late presentation to HIV/AIDS care presents serious health concerns, like increased transmission and high healthcare costs, increased mortality, early development of opportunistic infection, increased risk of antiretroviral therapy drug...

Adherence to HIV care and associated health functioning among youth living with HIV in Sub-Saharan Africa

2021

Older adolescents and young adults (youth) living with HIV (YLH) in sub-Saharan Africa (SSA) are at high risk for poor HIV treatment adherence and associated negative health outcomes including viral...

Epidemiological characterization and geographic distribution of human immunodeficiency virus/acquired immunodeficiency syndrome infection in North African countries

2021

BACKGROUND: Human immunodeficiency virus (HIV) infection is a major global public health concern. North African countries carry a disproportionate burden of HIV representing one of the highest rates in Africa....

Incidence and predictors of tuberculosis among HIV patients after initiation of antiretroviral treatment in Ethiopia: A systematic review and meta-analysis

2021

BACKGROUND: Tuberculosis is the oldest infectious disease and it is still the leading cause of morbidity and mortality worldwide. Even though several primary studies have been conducted on the incidence...

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