SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Cerebrospinal fluid immune markers and HIV-associated neurocognitive impairments: A systematic review

2021

HIV-1 is responsible for the development of a spectrum of cognitive impairments known as HIV-associated neurocognitive disorder (HAND). In the era of antiretroviral therapy (ART), HAND remains prevalent in people...

Interventions addressing depression and HIV-related outcomes in people with HIV

2021

PURPOSE OF REVIEW: People with HIV (PWH) are more likely to experience depression than those without HIV. Depression is not only distressing and interfering in and of itself, but it...

The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis

2021

BACKGROUND: The practice of involving people living with HIV in the development and provision of healthcare has gained increasing traction. Peer-support for people living with HIV is assistance and encouragement...

HIV prevalence among non-injecting people who use drugs and related factors in Iran: A systematic review and meta-analysis

2021

Issues: This systematic review aimed to provide an updated estimate on the prevalence of human immunodeficiency virus (HIV) infection among non-injecting people who use drugs (PWUD) and the various subgroups and...

Prevalence of oral lesions in patients with AIDS: A systematic review and meta-analysis

2021

Background Oral lesions are considered to be early clinical signs which may predict the progression of patients with acquired immune deficiency syndrome (AIDS). Due to the lack of a comprehensive...

Cause of hospitalization and death in the antiretroviral era in Sub-Saharan Africa published 2008–2018: A systematic review

2021

BACKGROUND: Worldwide despite the availability of antiretroviral therapy, human immunodeficiency virus/acquired immunodeficiency syndrome still causes morbidity and mortality among patients. In Sub-Saharan Africa, human immunodeficiency virus/acquired immunodeficiency syndrome remains a...

Harm reduction for smokers living with HIV

2021

Tobacco use is now a leading cause of death in people living with HIV in the USA. Increasing cessation rates in this group is a public health priority, yet the...

Barriers and facilitators of rendering HIV services by community health workers in sub-Saharan Africa: A meta-synthesis

2021

OBJECTIVES: To synthesise qualitative studies that address the barriers to and facilitators of providing HIV services by community health workers (CHWs) in sub-Saharan Africa (SSA). DESIGN: This meta-synthesis was guided...

A systematic review and meta-analysis of studies evaluating the effect of medication treatment for opioid use disorder on infectious disease outcomes

2021

The opioid epidemic has fueled infectious disease epidemics. We determined the impact of medications for opioid use disorder (MOUD) on treatment outcomes of opioid use disorder (OUD)-associated infectious diseases: antiretroviral...

Adolescents and young adults with early acquired HIV infection in the United States: Unique challenges in treatment and secondary prevention

2021

INTRODUCTION: Worldwide, children who acquired human immunodeficiency virus (HIV) at an early age, either perinatally or through blood transfusion, are reaching adolescence and adulthood due to successful antiretroviral treatment (ART)....

HIV prevalence among men who have sex with men in Iran: A systematic review and meta-analysis

2021

Background: The need for informed policymaking highlights the importance of data on human immunodeficiency virus (HIV) prevalence on key populations. In this systematic review and meta-analysis, we aimed to provide...

Purely behavioral: A scoping review of nonpharmacological behavioral and lifestyle interventions to prevent cardiovascular disease in persons living with HIV

2021

Cardiovascular disease (CVD) is the leading cause of death in the United States, accounting for 900,000 deaths annually. People living with HIV are at a higher risk of developing CVD....

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