SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Comparative efficacy of antifungal agents used in the treatment of oropharyngeal candidiasis among HIV-infected adults: A systematic review and network meta-analysis

2021

The objective of this study was to assess the comparative efficacy and safety of different antifungal agents used for the treatment of oropharyngeal candidiasis (OPC) in adult patients with HIV....

A systematic review and meta-analysis of mortality in anal cancer patients by HIV status

2021

Advances in HIV treatments have resulted in life expectancies among people with HIV (PWH) that are similar to people without HIV (non-PWH), provided that PWH have access to these treatments....

Design, analysis, and reporting of pilot studies in HIV: A systematic review and methodological study

2021

BACKGROUND: Pilot studies are essential in determining if a larger study is feasible. This is especially true when targeting populations that experience stigma and may be difficult to include in...

Approaches to transitioning women into and out of prevention of mother-to-child transmission of HIV services for continued ART: A systematic review

2021

Introduction: Women living with HIV are required to transition into the prevention of mother-to-child transmission of HIV (PMTCT) services when they become pregnant and back to ART services after delivery....

A review of reported cases of HIV pre-exposure prophylaxis failure with resultant breakthrough HIV infections

2021

OBJECTIVES: Early randomized controlled trials (RCTs) have confirmed high efficacy of pre-exposure prophylaxis (PrEP) for preventing HIV infection in men who have sex with men (MSM) with high HIV exposure...

A systematic review of the social network strategy to optimize HIV testing in key populations to end the epidemic in the United States

2021

The United States (U.S.) has a plan to end the HIV epidemic by 2030. The plan’s first pillar prioritizes HIV testing. Social Network Strategy (SNS) is an intervention to reach...

Risk of adverse coronavirus disease 2019 outcomes for people living with HIV

2021

OBJECTIVE: To assess whether people living with HIV (PLWH) are at increased risk of coronavirus disease 2019 (COVID-19) mortality or adverse outcomes, and whether antiretroviral therapy (ART) influences this risk....

Recurrent TB: a systematic review and meta-analysis of the incidence rates and the proportions of relapses and reinfections

2021

Background: A recurrent tuberculosis (TB) episode results from exogenous reinfection or relapse after cure. The use of genotyping allows the distinction between both. Methods: We did a systematic review and meta-analysis, using four...

Global estimate of phenotypic and genotypic ganciclovir resistance in cytomegalovirus infections among HIV and organ transplant patients; A systematic review and meta-analysis

2021

Human cytomegalovirus (CMV), an opportunistic pathogen belonging to Herpesviridae family, is considered as one of the major causes of morbidity and mortality among wide variety of patients, particularly in transplant...

Prevalence of transmitted resistance to non-nucleoside reverse transcriptase inhibitors in European and North American countries over 20 years: An updated meta-analysis

2021

The prevalence of transmitted non-nucleoside reverse transcriptase inhibitor (NNRTI) resistance around the world has been estimated up to 2010. Treatment recommendations have since evolved from NNRTIs to integrase strand inhibitors...

Acceptability and uptake of HIV self-testing in emergency care settings: A systematic review and meta-analysis

2021

Background: Emergency departments (ED) interface with large numbers of patients that are often missed by conventional HIV testing approaches. ED-based HIV self-testing (HIVST) is an innovative engagement approach which has potential...

Effect of community-based interventions targeting female sex workers along the HIV care cascade in sub-Saharan Africa: A systematic review and meta-analysis

2021

BACKGROUND: Female sex workers are extremely vulnerable and highly susceptible to being infected with human immunodeficiency virus. As a result, community-based targeted interventions have been recommended as one of the...

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