SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Better together?: A systematic review of he effectiveness of HIV prevention interventions that build or strengthen social ties

2025

Although social relationships impact health and social dynamics play a key role in shaping HIV vulnerability, results from intentional efforts to build or strengthen social relationships have not been synthesized...

Single-session interventions to enhance HIV outcomes among adolescents and young adults: A systematic scoping review and implications for integrating HIV and mental health services

2025

Significant progress has been made in HIV prevention and treatment for adolescents and young adults (AYA), but integrating mental healthcare remains essential to address risks and improve treatment engagement. Single-session...

Prevalence of opportunistic bacterial infections (tuberculosis and pneumonia) among people with HIV in Ethiopia: Systematic review and meta-analysis

2025

BACKGROUND: Individuals with weakened immune systems, such as those living with Human Immunodeficiency Virus (HIV), are more vulnerable to opportunistic bacterial infections, which include tuberculosis and pneumonia. This systematic review...

Long-acting injectable cabotegravir and rilpivirine in observational cohort studies: A systematic review on virological failure, resistance and re-suppression outcomes in virally suppressed individuals living with HIV

2025

Introduction Randomized controlled trial evidence suggests that long‐acting injectable (LA‐I) cabotegravir and rilpivirine (CAB+RPV) has similar virological failure (VF) rates to daily oral therapy, but clinical practice evidence is lacking....

Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: An individual data-based meta-analysis of 24 prospective studies

2025

The only current strategy to test efficacy of novel interventions for sustained HIV control without antiretroviral therapy (ART) among people with HIV (PWH) is through an analytical treatment interruption (ATI)....

Leveraging U=U in interventions for Black women living with HIV: A scoping review and call to action

2025

Despite significant reductions in the incidence and prevalence of human immunodeficiency virus (HIV) over recent decades, certain subgroups continue to experience disproportionate HIV-related health disparities. Cisgender Black women, in particular,...

Prevalence of HIV/syphilis co-infection among men who have sex with men in China: A systematic review and meta-analysis

2025

Background Men who have sex with men (MSM) are key populations for HIV and syphilis infection, and co-infection with both diseases significantly increases health risks. However, the co-infection of HIV/syphilis...

Development of research on HIV-associated neurocognitive disorder and emerging trends: a visualization analysis via CiteSpace

2025

BACKGROUND: In the combination antiretroviral therapy era, HIV-associated neurocognitive disorder (HAND) is still widespread among HIV-infected individuals. However, there is no effective treatment for HAND, and the exact pathogenic mechanism...

Transition to adult care for young people living with HIV

2025

Purpose of Review The purpose of this narrative review is to delineate the challenges of transitioning young people living with HIV (YPLHIV) to adult-based care and to review recent literature...

Evaluating HIV drug resistance in the Middle East and North Africa and its associated factors: A systematic review

2025

OBJECTIVE: One of the obstacles to achieving successful treatment of HIV infections is the development and spread of mutations linked to resistance. Thus, it is important to monitor the prevalence...

Body image among people living with HIV: A systematic review

2025

OBJECTIVES: The aim of this systematic review was to analyse, synthesise and review existing research on body image among people living with HIV (PLWH). Specifically, the review investigated the relationship...

Pharmacokinetic adaptations in pregnancy: Implications for optimizing antiretroviral therapy in HIV-positive women

2025

Pregnancy introduces significant physiological changes that alter the pharmacokinetics (PK) of antiretroviral therapy (ART), impacting its safety and efficacy in HIV-positive women. Optimizing ART during pregnancy is critical to maintaining...

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