SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Determination of depression prevalence in pregnant women living with HIV aged 18 years and older: A meta-analysis study

2025

BACKGROUND: Pregnant women living with HIV are known to be at higher risk of depression than pregnant women without HIV. Accompanied by a systematic literature review, the aim of this...

Global prevalence of advanced HIV disease in healthcare settings: A rapid review

2025

Introduction Recent studies have indicated a high enduring burden of advanced HIV disease, but estimates across regions and settings are lacking. The aim of this study was to estimate the...

The burden of HPV infections and HPV-related diseases among people with HIV: A systematic literature review

2025

Human papillomavirus (HPV) is associated with a significant global burden of precancerous lesions and cancer. People with HIV (PWH) are at higher risk of HPV infection and HPV‐related diseases. This...

Adherence definitions, measurement modalities, and psychometric properties in HIV, diabetes, and nutritional supplementation studies: A scoping review

2025

Measuring adherence has been a priority for researchers to help inform effective care for patients regularly consuming medications for chronic conditions. As a widely accepted “gold standard” adherence measure or...

What has been studied about attitudes and social stigma towards HIV/AIDS? A global bibliometric study with correlations on global health HIV-related indicators

2025

Introduction: This study aimed to assess, through health metrics and bibliometric analysis, the global research on attitudes and social stigma of people living with HIV/AIDS and to identify research findings,...

The diagnostic significance of the C-reactive protein (CRP) in HIV/TB coinfection: A systematic review and meta-analysis

2025

BackgroundDrug-resistant Mycobacterium tuberculosis strains have challenged efforts to combat tuberculosis (TB), a major global killer. C-reactive protein (CRP) shows promise as a biomarker for TB screening, particularly in HIV-positive cases,...

Prevalence of common mental disorders and sleep disorder among adolescents and young adults with HIV: A systematic review and meta-analysis

2025

OBJECTIVE: Adolescents and young adults (AYA) with HIV are a population at high risk of experiencing mental issues and sleep disorder. We aim to summarise the global prevalence and risks...

HIV post-exposure prophylaxis in community settings and by lay health workers or through task sharing: A systematic review of effectiveness, case studies, values and preferences, and costs

2025

INTRODUCTION: Post-exposure prophylaxis (PEP) for HIV prevention has been inadequately promoted, provided and used. Expanded access and task sharing could increase the HIV prevention impact of PEP, but scientific evidence...

Urgent focus on the surgical risks of people living with HIV: A systematic review and meta-analysis

2025

With the widespread promotion and application of antiretroviral therapy in clinical practice, people living with HIV (PLWH) have the potential to live as long as non-HIV people and the probability...

HIV-1 Drug Resistance in Children and Implications for Pediatric Treatment Strategies: A Systematic Review and Meta-analysis

2025

INTRODUCTION: Failure in the prevention of mother-to-child HIV transmission (PMTCT) and pediatric treatment challenges led to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children with HIV (CWHIV)....

Barriers to retention in care among adults with HIV in developed countries: An integrative review

2025

Focusing on factors hindering viral suppression is essential for improving the health outcomes of people with Human Immunodeficiency Virus (HIV) and working towards ending the HIV/AIDS epidemic. The aim of...

Use of behavior change techniques in digital HIV prevention programs for adolescents and young people: Systematic review

2025

BACKGROUND: HIV infections have caused severe public health and economic burdens to the world. Adolescents and young people continue to constitute a large proportion of newly diagnosed HIV cases. Digital...

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