SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effect of donor exclusion criteria on blood safety and volume of donations: A systematic review of modelling studies

2026

Objective To assess the effect of easing bans and deferral policies on blood donation from men who have sex with men on blood safety and volume from modelling studies. Methods We searched...

Prevalence of HIV and hepatitis B co-infection in Nigeria: A systematic review and meta-analysis

2026

Introduction Hepatitis B virus (HBV) and Human Immunodeficiency virus (HIV) infections are both major public health concerns in sub-Saharan Africa. Co-infection with these virus accelerates liver disease progression, increases hepatotoxicity,...

Housing instability as a barrier to HIV viral suppression: Evidence from a U.S. systematic review and meta-analysis

2026

Housing instability and homelessness remain pervasive structural determinants of poor HIV outcomes in the United States. People living with HIV (PLWH) who experience homelessness face intersecting barriers, including stigma, behavioral...

Impact of dolutegravir-based regimens on patient satisfaction and quality of life among people living with HIV: A systematic review and meta-analysis

2026

Background Despite the global scale up of dolutegravir (DTG)-based regimens as the preferred first-line therapy for persons living with HIV (PLHIV), no comprehensive evidence exists on its effect on patient-reported...

Systematic scoping review on HIV services for males in Sub-Saharan Africa: Access, barriers, and research gaps

2026

BACKGROUND: Access to HIV services among men and boys in Sub-Saharan Africa is a significant public health challenge, exacerbated by cultural norms surrounding masculinity. This scoping review systematically investigates disparities...

Prevalence and associated factors of ICD/DSM-diagnosed depressive disorders among people living with HIV: A systematic review and meta-analysis

2026

Background: Depressive disorders are highly prevalent among people living with HIV (PLWH), severely impairing quality of life and antiretroviral therapy (ART) adherence. While ART advances call for reassessing depressive disorders among...

Youth advisory board engagement in HIV research in low- and middle-income countries: A scoping review and additional youth perspectives

2026

Background. Engaging young people (10–24 years old) in research has been shown to improve the uptake and impact of HIV interventions in youth. However, how youth are engaged in Youth...

Prevalence of loneliness and social isolation among people living with HIV: A systematic review and meta-analysis

2026

Design A systematic review and meta-analysis. Data Sources PubMed, Cochrane Library, SciELO Citation Index (via Web of Science), Scopus, Embase, PsycArticles, and Cumulative Index to Nursing and Allied Health Literature...

The impact of APOE ε4 on cognitive performance in adults with HIV: A systematic review and meta-analysis

2026

Objective: With a rapidly aging population living with HIV that may face a double-hit of neuroHIV and Alzheimer’s disease, the objective of this meta-analysis was to evaluate the impact of...

Effectiveness of friendship bench in alleviating anxiety and depression symptoms among people living with HIV and high-risk populations: A systematic review and meta-analysis

2026

This systematic review and meta-analysis evaluated the Friendship Bench (FB) intervention’s efficacy in relieving anxiety and depression among people living with HIV (PLHIV) and high-risk populations, explored intervention effect heterogeneity,...

Disparities in awareness, willingness and uptake of biomedical HIV prevention among bisexual and gay men: A systematic review and meta-analysis

2026

INTRODUCTION: The field of HIV/STI prevention research has primarily focused on gay men, leaving bisexual men overshadowed in broader discussions on sexual minority men’s health. Although also at increased risk...

Effectiveness of differentiated antiretroviral therapy delivery models for stable persons living with HIV in Africa: A systematic review and meta-analysis

2026

Introduction: Fundamental progress has been made in HIV care, and one of the major advances was the implementation of Differentiated Service Delivery (DSD) models. DSD models are important in reducing cost...

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