SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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HIV risk behavior and associated factors among people living with HIV/AIDS in Ethiopia: A systematic review and meta-analysis

2022

BACKGROUND: HIV risk behavior among people living with HIV/AIDS (PLWHA) is a major public health concern as it increases HIV transmission. In Ethiopia, findings regarding HIV risk behavior have been...

Characterizing the impact of the COVID-19 pandemic on HIV PrEP care: A review and synthesis of the literature

2022

The global COVID-19 pandemic and associated lockdown measures have caused disruptions to sexual health services and created additional barriers to the continuity of HIV pre-exposure prophylaxis (PrEP) among key populations....

Psychiatric disorders in perinatally HIV-exposed, uninfected children: A systematic review

2022

The population of perinatally HIV-exposed but uninfected (HEU) children is growing rapidly globally. However, perinatal HIV and antiretroviral (ARV) medicine exposure in HIV-uninfected children has raised concerns about HEU children’s...

The innovative use of qualitative and mixed methods research to advance improvements along the HIV prevention and care continua

2022

PURPOSE OF REVIEW: Despite enormous advances in prevention and care modalities, HIV continues to burden populations around the globe and is largely driven by social and behavioral processes. Mixed methods...

Impact of combined antiretroviral therapy on metabolic syndrome components in adult people living with HIV: A literature review

2022

The development of metabolic derangements as a result of HIV treatment has been an important area of research since the introduction of zidovudine in the 1980’s. Antiretroviral therapy has intensely...

A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection

2022

Integrase strand transfer inhibitors (INSTIs) have improved the treatment of human immunodeficiency virus (HIV). There are currently four approved for use in treatment-naA_ve individuals living with HIV; these include first...

Research synthesis, HIV prevention response, and public health: CDC’s HIV/AIDS prevention research synthesis project

2022

OBJECTIVE: Research synthesis, through qualitative or quantitative systematic reviews, allows for integrating results of primary research to improve public health. We examined more than 2 decades of work in HIV...

Effects of interleukin-10 -1082G/A and -592C/A gene polymorphisms on the risk of human immunodeficiency virus-1 infection: An updated meta-analysis

2022

This paper has aimed to review the available evidence on the association between Interleukin (IL) -10 -1082G/A, -592C/A gene polymorphisms and the risk of human immunodeficiency virus-1(HIV-1) infection. The data...

Incentive-based human immunodeficiency virus screening in low- and middle-income countries: A systematic review

2022

BACKGROUND: The majority of new human immunodeficiency virus (HIV) infections that occur worldwide are in sub-Saharan Africa. While recent gains have been made in many low- and middle-income countries (LMICs),...

Public health implications of adapting HIV pre-exposure prophylaxis programs for virtual service delivery in the context of the COVID-19 pandemic: A systematic review

2022

BACKGROUND: The novel coronavirus disease-19 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) threatens to disrupt global progress towards HIV epidemic control. Opportunities exist to leverage ongoing...

Systematic review: Development of a person-centered care framework within the context of HIV treatment settings in sub-Saharan Africa

2022

OBJECTIVES: Person-centred care (PCC) meets the needs of individuals by increasing convenience, providing supportive and culturally appropriate services to diverse populations, and engaging families, communities, and stakeholders in planning and...

Prevalence and determinants of suicidal ideation and suicide attempt in people with human immunodeficiency virus in Africa: A systematic review

2022

BACKGROUND: People with human immunodeficiency virus (HIV) are at higher risk of suicidal ideation and suicide attempts. We reviewed the literature for the prevalence and determinants of suicidal ideation and...

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