SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Global health initiatives and the combat of HIV/AIDS on the African continent: A scoping review

2025

The aim is to identify, in the literature, the influence of Global Health Initiatives (GHI) on the HIV combat in Africa. A scoping review was carried out in March 2023...

Assessing the impact of digital communication tools on oral PrEP adherence: A systematic review and meta-analysis

2025

This systematic review and meta-analysis evaluated the effect of digital communication tools (e.g., text message reminders) on improving daily oral HIV pre-exposure prophylaxis (PrEP) adherence. Searching PubMed, Embase, Web of...

What services, interventions and support are available for people with HIV in England to manage their overall health and wellbeing? A scoping review

2025

OBJECTIVES: The average age of a person living with HIV in high-income countries is increasing, as are rates of multimorbidity and frailty. To meet these needs, existing services must adapt....

Rapid start with bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) as initial treatment in people with human immunodeficiency virus-1 (HIV-1): A systematic literature review of clinical and patient-reported outcomes

2025

BACKGROUND: Treatment guidelines recommend rapid antiretroviral therapy (ART) initiation among eligible people with HIV to improve treatment outcomes and reduce HIV transmission. Bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF), an integrase strand transfer inhibitor-based...

Characterization and risk stratification of coronary artery disease in people living with HIV: A global systematic review

2025

Background Coronary artery disease (CAD) is a leading cause of mortality among people living with HIV (PLWH). Risk stratification remains inconsistent due to geographic disparities, ART-related metabolic effects, and overreliance...

Gut microbiota of sub-Saharan Africa infants exposed to antiretroviral therapy: Scoping review

2025

Background Antiretroviral (ARV) exposure influences the early-life gut microbiota in regions with high human immunodeficiency virus (HIV) burdens. Understanding how ARV drugs affect the infant gut microbiota is important for...

HIV self-testing and partner notification strategies for key populations in low- to upper-middle-income countries: A mixed-methods systematic review

2025

BACKGROUND: HIV self-testing (HIVST) enhances case diagnosis, but information on its integration for index testing to partner notification is limited. Assessing the acceptability and feasibility of index HIVST and partner...

Determinants of HIV pre-exposure prophylaxis (PrEP) use among men who have sex with men (MSM) living in rural areas of the United States: A scoping review framed by the PrEP care continuum

2025

BACKGROUND: HIV pre-exposure prophylaxis (PrEP) is a highly effective intervention to prevent HIV transmission among men who have sex with men (MSM). Despite its effectiveness, PrEP uptake and adherence among...

Complications due to HIV in patients undergoing total joint arthroplasty: A systematic review and meta-analysis

2025

Background: HIV infection in patients undergoing Total joint arthroplasty (TJA) results in adverse postoperative outcomes. However, there are uncertain data regarding the extent of involvement of HIV in TJA and the...

Predictors of anemia among HIV-infected children in Ethiopia: Systematic review and meta-analysis

2025

Anemia continues to be one of the common complications among HIV-infected children. In Ethiopia, though there is a systematic review and meta-analysis study on anemia among HIV-infected children, it only...

A scoping review: Forced/coerced sterilization as a socio-cultural risk factor for sexually transmitted HIV for older Black women

2025

Understanding socio-cultural factors that influence older (age 50 and up) Black women’s risk for sexually transmitted HIV has often been absent from policies and programs. This scoping review asked: What...

Nutritional status of adult people living with HIV: A narrative review

2025

BACKGROUND: The interaction between HIV infection, nutrition and immune system functioning is intricate, leading, in many cases, to a cycle of poor health outcomes. Despite the widespread use of highly...

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