SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Pre-exposure prophylaxis care engagement among men who have sex with men in the United States during the COVID-19 pandemic: A scoping review

2025

The COVID-19 pandemic substantially impacted the pre-exposure prophylaxis (PrEP) care continuum among men who have sex with men (MSM). While PrEP use during the pandemic has been studied, regional differences...

The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers

2025

BACKGROUND: Human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection present a significant impact on women’s health globally, especially in immunocompromised individuals. HIV-induced immunosuppression promotes the persistence of high-risk HPV...

Growth and body composition of adolescents and young adults with perinatal HIV infection: A systematic review and meta-analysis

2025

Introduction: Approximately 1.3 million pregnancies are exposed to HIV perinatally each year, with transmission rates ranging from 4 to 21%, despite 85% antiretroviral therapy (ART) coverage among pregnant women. While ART...

Assessment tools for evaluating pharmacy students’ knowledge on HIV prophylaxis: A scoping review

2025

OBJECTIVES: This study aimed to identify and evaluate instruments used to measure pharmacy students’ knowledge of HIV prophylaxis, focusing on both preexposure prophylaxis (PrEP) and postexposure prophylaxis. METHODS: A systematic...

Breast cancer clinical characteristics, management, and outcomes in women living with HIV/AIDS globally: A systematic review and meta-analysis

2025

Although associations between HIV and breast cancer (BC) have been investigated, the global literature remains inconsistent regarding clinical features and outcomes in HIV-positive patients. This study aims to clarify the...

Health educational interventions for adolescents living with HIV: A scoping review

2025

BACKGROUND: Adolescents living with HIV face unique challenges as they gain greater independence while transitioning into adulthood. They must adjust their self-management activities and take primary responsibility for their health,...

Impact of mHealth on enhancing pre-exposure prophylaxis adherence and strengthening the HIV prevention cascade among key populations: A systematic review and meta-analysis

2025

Background Good adherence to pre-exposure prophylaxis (PrEP) is critical for effective HIV prevention. Despite the growing awareness of PrEP, many individuals remain at a preliminary understanding stage and struggle to...

Extended-spectrum β-lactamase-producing Enterobacterales among people living with human immunodeficiency virus across the globe: A systematic review and meta-analysis

2025

Background People living with HIV are vulnerable to antibiotic-resistant bacterial infections because of frequent healthcare visits, the consumption of many antimicrobials, and the weakened immune system to fight infections. Our...

Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: A systematic review

2025

Background To stem rising fatal overdoses and other substance use/use disorder (SUD)-related harms, communities are turning to low-barrier harm reduction strategies, such as harm reduction-focused vending machines (VMs) that distribute...

Network meta-analytical investigations of the performance of HIV combination prevention strategies for Indigenous populations

2025

BACKGROUND: Indigenous populations worldwide face a disproportionate burden of HIV due to structural inequities, cultural marginalization, and limited access to health services. Despite growing recognition of the need for culturally...

The magnitude and patterns of acquired drug resistanace mutations and circulating HIV-1 subtypes in HIV patients in Tanzania, a systematic review and meta-analysis

2025

The emergence and spread of HIV drug resistance mutations (DRMs) pose a threat to current and future treatment options. To inform policy, this review aimed to determine the magnitude and...

Approaches used to monitor the effectiveness of community-led monitoring programmes: A scoping review to inform HIV programmes

2025

INTRODUCTION: Community-led monitoring (CLM) for HIV is a technique implemented by local community-led organizations and groups that systematically gather data about HIV services to advocate for improvement. This review was...

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