SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effects of probiotics on diarrhea and CD4 cell count in people living with HIV: A systematic review and meta-analysis

2021

Gastrointestinal probiotics play an important role in maintaining intestinal bacteria homeostasis. They might benefit people with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), which remains a global health challenge. However, there...

Recommendations for increasing physician provision of pre-exposure prophylaxis: Implications for medical student training

2021

There is growing evidence that pre-exposure prophylaxis (PrEP) prevents HIV acquisition. However, in the United States, approximately only 4% of people who could benefit from PrEP are currently receiving it,...

Oral candidiasis prevalence in human immunodeficiency virus-1 and pulmonary tuberculosis coinfection: A systematic review and meta-analysis

2021

BACKGROUND: Human immunodeficiency virus-1 (HIV-1) infected people are more likely to develop tuberculosis (TB), being the leading cause of death in HIV-1. Candida spp has emerged as potential pathogenic fungi...

Ethical considerations for research involving pregnant women living with HIV and their young children: A systematic review of the empiric literature and discussion

2021

BACKGROUND: The proper and ethical inclusion of PWLHIV and their young children in research is paramount to ensure valid evidence is generated to optimize treatment and care. Little empirical data...

The effects of MDR/RR-TB treatment on HIV disease: A systematic review of literature

2021

BACKGROUND: Multidrug-resistant or rifampicin-resistant tuberculosis (MDR/RR-TB) and human immunodeficiency virus (HIV) co-infection are a deadly combination. While evidence on the effects of HIV co-infection on MDR/RR-TB treatment outcomes is well-documented,...

The level of unmet need for family planning and its predictors among HIV-positive women in Ethiopia: A systematic review and meta-analysis

2021

BACKGROUND: Studies indicated that the need for family planning appears to be greater for human immuno-deficiency virus- (HIV-) positive women than the general population to reduce the risk of pediatrics...

A review of structural, process, and outcome measures for supervised consumption services

2021

A 2019 systematic review identified several types of outcomes from scientific literature that guide assessment of SCS, including: usage by high-risk individuals, safe injection practice, overdose management, uptake of treatment...

Prevalence of syphilis among men who have sex with men: A global systematic review and meta-analysis from 2000–20

2021

BACKGROUND: The WHO Global Health Sector Strategy aims to reduce worldwide syphilis incidence by 90% between 2018 and 2030. If this goal is to be achieved, interventions that target high-burden...

Intervening for HIV prevention and mental health: A review of global literature

2021

INTRODUCTION: Numerous effective HIV prevention options exist, including behaviour change interventions, condom promotion and biomedical interventions, like voluntary medical male circumcision and pre-exposure prophylaxis. However, populations at risk of HIV...

Anemia and thrombocytopenia in people living with HIV/AIDS: A narrative literature review

2021

Hematologic changes are frequent complications in people living with HIV/AIDS (PLWHA). Anemia and thrombocytopenia are the most frequent multifactorial hematologic abnormalities and are associated with a low quality of life...

Combination model in reducing HIV-related stigma: A systematic review

2021

OBJECTIVE: This article identifies and explains the various research models related to HIV stigma. METHODS: This systematic review is done using the PRISMA 2015 guidelines. Source of this review uses...

A scoping review investigating relationships between depression, anxiety, and the PrEP care continuum in the United States

2021

Men who have sex with men and transgender women in the United States are at increased risk for HIV and may benefit from pre-exposure prophylaxis (PrEP), a once-a-day pill to...

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