SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Systematic review exploring the burden of sexually transmissible infections and bloodborne viruses in refugees and asylum seekers: Insights to inform policy and practice

2025

BACKGROUND: In 2022, the number of refugees and asylum seekers (RAS) have reached an all-time high of 40.7 million globally. The surge in RAS, coupled with their limited access to...

Effectiveness of exercise on sarcopenia in HIV patients: A systematic review of current literature

2025

Exercise is vital in managing sarcopenia in people living with HIV (PLWH). This study explores the role of exercise in reducing sarcopenia in HIV patients. A systematic search of electronic...

The prevalence of low-level viraemia and its association with virological failure in people living with HIV: A systematic review and meta-analysis

2025

Low-level viraemia (LLV) following antiretroviral therapy (ART) in people living with HIV (PLWH) has not received sufficient attention. To the determine the prevalence of LLV and its association with virological...

Viral load suppression rate of third-line antiretroviral therapy and its association with gender among HIV patients after second-line treatment failure in Africa: A systematic review and meta-analysis

2025

INTRODUCTION: Previous works of literatures on the viral load suppression rate of third line antiretroviral therapy in Africa has produced inconsistent and inconclusive results, with rates varying between 62% and...

Prevalence of late HIV diagnosis and its impact on mortality: A comprehensive systematic review and meta-analysis

2025

Objectives: The late diagnosis of HIV infection plays a crucial role in accelerating the disease progression and increasing the risk of death in the HIV population. However, there remains no consensus...

The efficacy of Cotrimoxazole for the prevention of Pneumocystis jirovecii pneumonia among HIV-exposed and infected children: A systematic review

2025

BACKGROUND: HIV-related opportunistic infections like Pneumocystis jirovecii Pneumonia (PCP) remain a major contributor to child morbidity and mortality globally. PCP accounts for over 60% of AIDS in the first year...

Nutritional status of adult people living with HIV: A narrative review

2025

BACKGROUND: The interaction between HIV infection, nutrition and immune system functioning is intricate, leading, in many cases, to a cycle of poor health outcomes. Despite the widespread use of highly...

An international compendium of health state utilities in people with HIV: A systematic review

2025

Purpose: Measuring health-related quality of life across different health states for people with HIV (PWH) using direct or indirect preference-based values can inform decision-analytic models evaluating cost-effectiveness of different care strategies....

Social and structural determinants of health influencing HIV risk and participation across the HIV care cascade

2025

Key take-home messages

Evaluating the safety and efficacy of malaria preventive measures in pregnant women with a focus on HIV status: A systematic review and network meta-analysis

2025

Background and Objectives: Malaria poses significant threats to pregnant women, particularly in endemic regions. Preventive measures against it include insecticide-treated bed nets, intermittent preventive treatment, and various supplements. We aimed...

Prevalence of hepatitis B virus infection and its associated factors in Ethiopia: A recent systematic review and meta-analysis

2025

BACKGROUND: Hepatitis B virus (HBV) is one of the most common causes of chronic liver disease and is a growing concern in low-income countries, including Ethiopia. Different studies have been...

Patient-reported outcomes in clinical trials assessing the effectiveness of cabotegravir + rilpivirine long-acting injections as antiretroviral therapy: A systematic review

2025

Introduction: Human immunodeficiency virus-1 (HIV-1) continues to have ahigh global burden, with approximately 39.9 million people currently livingwith the virus. Despite the clinical success of antiretroviral therapy (ART),adherence remains a...

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