SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A mega-aggregation framework synthesis of the barriers and facilitators to linkage, adherence to ART and retention in care among people living with HIV

2021

BACKGROUND: People living with human immunodeficiency virus (PLHIV) struggle with the challenges of living with a chronic disease and integrating antiretroviral treatment (ART) and care into their daily lives. The...

Effectiveness of naltrexone treatment for alcohol use disorders in HIV: A systematic review

2021

BACKGROUND: Because alcohol use disorders (AUDs) in patients living with HIV/AIDS are associated with a reduction in therapeutic outcomes and increases the risk of morbidity/mortality, finding an appropriate pharmacotherapy treatment...

Gaps in knowledge about the vaccine coverage of immunocompromised children: A scoping review

2021

Immunocompromised children are at increased risk of severe illness from vaccine-preventable infections. However, inadequate vaccine coverage remains a concern. This scoping review sought to determine the current state of knowledge...

The role of phylogenetics in discerning HIV-1 mixing among vulnerable populations and geographic regions in sub-Saharan Africa: A systematic review

2021

To reduce global HIV-1 incidence, there is a need to understand and disentangle HIV-1 transmission dynamics and to determine the geographic areas and populations that act as hubs or drivers...

Association between HIV infection and hypertension: A global systematic review and meta-analysis of cross-sectional studies

2021

Background: Improved access to effective antiretroviral therapy has meant that people living with HIV (PLHIV) are surviving to older ages. However, PLHIV may be ageing differently to HIV-negative individuals, with...

The prevalence, etiological agents, clinical features, treatment, and diagnosis of HIV-associated oral candidiasis in pediatrics across the world: A systematic review and meta-analysis

2021

In HIV-infected pediatrics, oral candidiasis (OC) is a global issue of concern due to its association with dysphagia, malnutrition, and mortality. The present systematic review and meta-analysis are the first...

Sexual and reproductive health needs of young people living with HIV in low- and middle-income countries: A scoping review

2021

Background: Young people living with HIV(YPLWH) in low-and middle-income countries are entering adolescence and young adulthood in signifcant numbers. The majority of the HIV-related research on these young people has...

Cash transfers for HIV prevention: A systematic review

2021

BACKGROUND: Given the success of cash programs in improving health outcomes and addressing upstream drivers of HIV risk such as poverty and education, there has been an increasing interest in...

Global health facility-based interventions to achieve UNAIDS 90-90-90: A systematic review and narrative analysis

2021

To evaluate whether health facility-based HIV interventions align with UNAIDS 90-90-90 targets, we performed a systematic review through the lens of UNAIDS targets. We searched 11 databases, retrieving 5201 citations...

HIV and SARS-CoV-2 Co-Infection: What are the risks?

2021

The dramatic increase of the global pandemic of SARS-CoV-2 infection represents a critical issue that needs to be investigated to evaluate the associated risk factors for acquisition and worse outcome....

The OATH syndemic: Opioids and other substances, aging, alcohol, tobacco, and HIV

2020

PURPOSE OF REVIEW: Persons living with HIV (PLWH) are aging, continue to use alcohol and other substances, and experience age-associated adverse effects. We explore a new syndemic: OATH (opioids and...

Childhood sexual trauma and antiretroviral therapy adherence: A mixed-methods systematic review

2020

Childhood sexual abuse (CSA) has been shown to be more prevalent among populations living with HIV. Antiretroviral therapy (ART) adherence is crucial for populations living with HIV as it significantly...

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