SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Barriers and facilitators for early and exclusive breastfeeding in health facilities in Sub-Saharan Africa: A systematic review

2021

BACKGROUND: Sub-Saharan Africa carries a disproportionate burden of under-five child deaths in the world and appropriate breastfeeding practices can support efforts to reduce child mortality rates. Health facilities are important...

Mental health interventions for persons living with HIV in low- and middle-income countries: A systematic review

2021

INTRODUCTION: Addressing the intersection between mental health and HIV is critical for the wellbeing of persons living with HIV (PLWH). This systematic review synthesized the literature on mental health interventions...

Evidence on the effectiveness of community-based primary health care in improving HIV/AIDS outcomes for mothers and children in low- and middle-income countries: Findings from a systematic review

2021

BACKGROUND: The effectiveness of community-based primary health care (CBPHC) interventions in low- and middle-income countries (LMICs), especially for maternal, neonatal and child health, is well established. However, there has not...

A meta-analytic review of the effect of antiretroviral therapy on neurocognitive outcomes in adults living with HIV-1 in low-and middle-income countries

2021

HIV-associated neurocognitive impairment remains a challenge even in the era of antiretroviral therapy (ART). Over 90% of people living with HIV are in low- and middle-income countries. Hence, it is...

HIV response interventions that integrate HIV molecular cluster and social network analysis: A systematic review

2021

Due to improved efficiency and reduced cost of viral sequencing, molecular cluster analysis can be feasibly utilized alongside existing human immunodeficiency virus (HIV) prevention strategies. The goal of this paper...

Mapping evidence on predictors of adverse sexual and reproductive health outcomes among young women in South Africa: A scoping review

2021

BACKGROUND: Globally, most young women have an unmet need for sexual and reproductive health (SRH), which remains a public health concern. Identifying the predictors can help reduce this challenge. AIM:...

Stated preference research in reproductive and maternal healthcare services in sub-Saharan Africa: A systematic review

2021

BACKGROUND AND OBJECTIVE: Understanding the preferred choice of healthcare service attributes for women is important, particularly in sub-Saharan Africa where resources are constrained and improving reproductive and maternal healthcare services...

Assessing HIV and overdose risks for people who use drugs exposed to compulsory drug abstinence programs (CDAP): A systematic review and meta-analysis

2021

Background: Evidence supports integrating drug use treatment, harm reduction, and HIV prevention services to address dual epidemics of drug use disorders and HIV. These dual epidemics have spurred a rise in...

Global scoping review of HIV prevention research with transgender people: Transcending from trans-subsumed to trans-centred research

2021

INTRODUCTION: Globally, transgender populations are disproportionally impacted by HIV and effective HIV prevention interventions targeting these populations are critically needed. Such interventions require research focused on the specific needs and...

The dual burden of HIV infection and first-episode psychosis in Africa: A systematic review and meta-analysis

2021

A systematic review and meta-analysis was conducted to synthesize data on HIV prevalence in individuals with first-episode psychosis (FEP) and to provide an overview of the association of HIV with...

Efavirenz versus protease inhibitors in patients with HIV: A systematic review and meta-analysis

2021

Efavirenz- and protease inhibitor (PI)-based regimens remain viable options across the globe. We conducted a meta-analysis to compare the effectiveness of efavirenz-based regimens relative to PI-based regimens. EMBASE, PubMed, Cochrane,...

Effectiveness of GeneXpertAr in the diagnosis of tuberculosis in people living with HIV/AIDS

2021

OBJECTIVE: To identify and synthesize the scientific knowledge produced regarding the effectiveness of the GeneXpert test in the diagnosis of pulmonary tuberculosis (TB) in people living with HIV/AIDS. METHODS: Integrative...

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