SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Prevalence, healthcare costs and management of non-communicable diseases in people living with human immunodeficiency virus: A scoping review

2020

BACKGROUND: Coexistence of human immunodeficiency virus (HIV) and non-communicable diseases (NCDs) is an important public health issue of increasing concern. However, the prevalence, healthcare costs and management protocols for NCDs...

The effect of tenofovir disoproxil fumarate on bone mineral density: A systematic review and meta-analysis

2020

BACKGROUND: We conducted a systematic review and meta-analysis (CRD#42017070552) to quantify the impact of oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) on bone mineral density (BMD) and the risk of osteoporosis, low...

Residual or recurrent precancerous lesions after treatment of cervical lesions in human immunodeficiency virus-infected women: A systematic review and meta-analysis of treatment failure

2020

BACKGROUND: Screening and treating premalignant cervical lesions (cervical intraepithelial neoplasia 2+ [CIN2+]) is an effective way to prevent cervical cancer, and recommendations exist for the monitoring of treatment success. Yet,...

Transmission dynamics in tuberculosis patients with human immunodeficiency Virus: A systematic review and meta-analysis of 32 observational studies

2020

BACKGROUND: There are large knowledge gaps on the transmission dynamics of Mycobacterium tuberculosis in settings where both tuberculosis and HIV are endemic. We aimed to assess the infectiousness of tuberculosis...

Are Candida albicans isolates from the oral cavity of HIV-infected patients more virulent than from non-HIV-infected patients? Systematic review and meta-analysis

2020

Candida albicans is the main causative agent of oral lesions in HIV-infected patients and its oral colonization is a potential source of systemic dissemination. Although the high prevalence of lesions...

Diagnostic infectious diseases testing outside clinics: A global systematic review and meta-analysis

2020

BACKGROUND: Most people around the world do not have access to facility-based diagnostic testing, and the gap in availability of diagnostic tests is a major public health challenge. Self-testing, self-sampling,...

Religion, faith, and spirituality influences on HIV prevention activities: A scoping review

2020

INTRODUCTION: Strategies to increase uptake of next-generation biomedical prevention technologies (e.g., long-acting injectable pre-exposure prophylaxis (PrEP)) can benefit from understanding associations between religion, faith, and spirituality (RFS) and current primary...

A realist systematic review of stigma reduction interventions for HIV prevention and care continuum outcomes among men who have sex with men

2020

While stigma associated with human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) is well recognized, there remains relatively limited intervention data on effective stigma reduction...

Screening algorithms to reduce burden of pediatric HIV testing: A systematic review and meta-analysis

2020

BACKGROUND: The accuracy of symptom screening to identify children eligible for further HIV testing in generalized epidemics has been examined in several studies. We performed a systematic review and meta-analysis...

Cryptosporidium infection increases the risk for chronic diarrhea among people living with HIV in southeast Asia: A systematic review and meta-analysis

2020

We conducted a systematic review research and meta-analysis to reveal the relationship between the risk of chronic diarrhea and Cryptosporidium infection in people living with HIV in Southeast Asia. We...

Systematic review of peer-reviewed literature on global condom promotion programs

2020

Background: Globally, 1.7 million people were newly infected with HIV in 2018. Condoms are inexpensive, cost-effective, reduce HIV/STI incidence, morbidity, mortality, and unintended pregnancies, and result in health care cost...

Coinfection of Tuberculosis and HIV in Nigeria: A Systematic Review and Meta-analysis

2020

Tuberculosis (TB) and HIV/AIDS are major public health issues globally. The burden of these diseases is particularly significant in Nigeria due to the high TB and HIV/AIDS prevalence. This meta-analysis...

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