SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Clinical events associated with poor CD4(+) T-cell recovery in people living with HIV following ART: A systematic review and meta-analysis

2025

Background: Antiretroviral therapy (ART) has significantly improved outcomes for people living with HIV (PLWH), but poor CD4+ T-cell recovery remains a challenge. This study aimed to evaluate the relationship between poor CD4+ T-cell...

Growth patterns of HIV-exposed and -unexposed infants in African countries: A systematic review and meta-analysis

2025

Background/Objectives: The purpose of this study is to understand the prevalence and odds of poor growth patterns among HIV-exposed but uninfected (HEU) versus HIV-unexposed (HUU) infants in the era of antiretroviral...

The prevalence of nonalcoholic fatty liver disease in people living with HIV: A systematic review and meta-analysis

2025

Background: Owing to long-term antiretroviral therapy (ART), the incidence of non-HIV-related chronic diseases is increasing, and liver disease is the leading cause of increased AIDS mortality. Moreover, the prevalence of NAFLD...

Comprehensive appraisal of the association between sexually transmitted infections and prostate cancer: A scoping review of empirical studies, reviews, and meta-analyses

2025

We performed a scoping review on the association of sexually transmitted infections (STIs) with prostate cancer and identified knowledge gaps. Searching four databases (Medline, Embase, Scopus, and Cochrane) identified 286...

Four decades of overdose prevention centres: Lessons for the future from a realist review

2025

BACKGROUND: Overdose prevention centres (OPCs) are spaces where people can consume previously obtained illicit drugs under the supervision of staff who can intervene to prevent and manage overdose.AÿThey have been...

Improving communication: A narrative synthesis of interventions for HIV disclosure to pediatric populations

2025

PURPOSE OF REVIEW: HIV remains a significant global public health concern, affecting millions worldwide, including children. Disclosure of HIV status to infected children holds several benefits, yet rates of disclosure...

Technologies for healthy lifestyle in people with HIV: A systematic review

2025

OBJECTIVE: to analyze clinical trials that assessed the effectiveness of technologies for healthy lifestyles in people with HIV. METHOD: A systematic review, conducted in five databases, with association of controlled...

Sexually transmitted and blood-borne infections in transgender and non-binary people in Canada: A scoping review

2025

In the 2021 census, 100,815 people in Canada aged 15 and older identified as transgender or non-binary. Globally, transgender people are disproportionately burdened by several Sexually Transmitted and Blood-Borne Infections...

Systematic review exploring the burden of sexually transmissible infections and bloodborne viruses in refugees and asylum seekers: Insights to inform policy and practice

2025

BACKGROUND: In 2022, the number of refugees and asylum seekers (RAS) have reached an all-time high of 40.7 million globally. The surge in RAS, coupled with their limited access to...

Breastfeeding knowledge, attitudes and practices of HIV-positive women in Africa: A systematic review

2025

BACKGROUND: Breastfeeding is essential for ensuring the health and survival of children, particularly in regions where diarrhoea, pneumonia and malnutrition are common causes of child mortality. In sub-Saharan Africa, over...

Maternal HIV infection and antiretroviral therapy in pregnancy: Implications for vertical transmission, fetal safety, and long-term infant outcomes

2025

HIV mother-to-child transmission (MTCT) continues to pose a significant public health challenge, especially in regions with limited resources, although the worldwide distribution of antiretroviral therapy (ART) has drastically lowered the...

Prevalence of human papillomavirus and genotype distribution in Chinese men: A systematic review and meta-analysis

2025

BACKGROUND: Human papillomavirus (HPV) vaccination represents a cost-effective strategy for preventing HPV-related diseases across genders. However, the HPV vaccine has not been approved for mainland Chinese males, and the comprehensive...

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