SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Sexual health interventions delivered to participants by mobile technology: A systematic review and meta-analysis of randomised controlled trials

2021

Background: The use of mobile technologies to prevent STIs is recognised as a promising approach worldwide; however, evidence has been inconclusive, and the field has developed rapidly. With about 1...

The effects of HIV self-testing on the uptake of HIV testing, linkage to antiretroviral treatment and social harms among adults in Africa: A systematic review and meta-analysis

2021

INTRODUCTION: HIV infection is still a global public health problem. More than 75% of HIV-infected people are in Africa, and up to 54% are unaware of their HIV status, limiting...

Risk factors and predictors associated with the severity of COVID-19 in China: A systematic review, meta-analysis, and meta-regression

2021

Since December 2019, the pneumonia cases infected with 2019 novel coronavirus have appeared, posing a critical threat to global health. In this study, we performed a meta-analysis to discover the...

Impact of COVID-19 in patients with concurrent co-infections: A systematic review and meta-analyses

2021

The burden and impact of secondary superadded infections in critically ill coronavirus disease 2019 (COVID-19) patients is widely acknowledged. However, there is a dearth of information regarding the impact of...

Should we care about Plasmodium vivax and HIV co-infection? A systematic review and a cases series from the Brazilian Amazon

2021

BACKGROUND: Malaria and HIV are two important public health issues. However, evidence on HIV-Plasmodium vivax co-infection (HIV/PvCo) is scarce, with most of the available information related to Plasmodium falciparum on...

Human Immunodeficiency Virus Infection and Incident Heart Failure: A Meta-analysis of Prospective Studies

2021

OBJECTIVES: To systematically analyze available prospective evidence on the association between HIV infection and incident heart failure (HF). METHODS: A systematic search of PubMed, EMBASE, Web of Science, and manual...

Isoniazid preventive therapy plus antiretroviral therapy for the prevention of tuberculosis: A systematic review and meta-analysis of individual participant data

2021

Background: Isoniazid preventive therapy prevents active tuberculosis in people with HIV, but previous studies have found no evidence of benefit in people with HIV who had a negative tuberculin skin...

Association of schistosomiasis and HIV infections: A systematic review and meta-analysis

2021

BACKGROUND: Female genital schistosomiasis (FGS) affects up to 56 million women in sub-Saharan Africa and may increase risk of HIV infection. METHODS: To assess the association of schistosomiasis with HIV...

Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: A narrative overview

2021

BACKGROUND: South Africa, with one of the highest HIV prevalences in the world, introduced the universal test and treat (UTT) programme in September 2016. Barriers to sustained viral suppression may...

Oral candidiasis prevalence in human immunodeficiency virus-1 and pulmonary tuberculosis coinfection: A systematic review and meta-analysis

2021

BACKGROUND: Human immunodeficiency virus-1 (HIV-1) infected people are more likely to develop tuberculosis (TB), being the leading cause of death in HIV-1. Candida spp has emerged as potential pathogenic fungi...

Prevalence of HIV, HCV, and HBV in Central Asia and the Caucasus: A Systematic Review

2021

BACKGROUND: HIV, Hepatitis C virus (HCV), and hepatitis B virus (HBV) are substantial public health threats in the region of Central Asia and the Caucasus, where the prevalence of these...

Change in condom use in populations newly aware of HIV diagnosis in the United States and Canada: A systematic review and meta-analysis

2021

HIV-infected individuals “aware” of their infection are more likely to use condoms, compared to HIV-infected “unaware” persons. To quantify this likelihood, we undertook a systematic review and meta-analysis of U.S....

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