SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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A scoping review of the methods, content, and populations of rural LGBTQ health research since the new millennium

2026

INTRODUCTION: This scoping review mapped the population characteristics, methodologies, content, and publishing trends of primary research focused on rural LGBTQ individuals since the year 2000. METHODS: We conducted a search...

The impact of human immunodeficiency virus coinfection on mpox patients during the 2022 global outbreak: A systematic review and meta-analysis based on comparative observational studies

2026

Background The mpox outbreak in 2022 posed a new challenge to the medical system. We aimed to study the impact of human immunodeficiency virus (HIV) coinfection on mpox patients. Methods This...

Implementation of point of care HIV viral load monitoring for people living with HIV in low- and middle-income countries: A systematic review on implementation research outcomes

2026

BACKGROUND: Viral load monitoring has rapidly increased among people living with HIV(PLHIV) in low- and middle-income countries (LMICs), resulting in an increased laboratory workload. The use of innovative Point of...

Cancer in older adults living with HIV

2026

Key take-home messages

A systematic review and meta-analysis on the association between antiretroviral therapy refill type and viral suppression

2026

To reduce barriers to viral suppression, people living with HIV (PLWH) are placed on multi-month dispensing (MMD)of antiretroviral therapy medication. However, there are concerns about viral rebound following MMD initiation,...

A synthesis of dimensions of wellbeing among adolescents and young people living with HIV from sub-Saharan Africa for measurement in economic evaluation: A qualitative overview of reviews

2026

Background Adolescents and young people living with HIV (AYPLHIV) in sub-Saharan Africa (SSA) face intersecting structural and psychosocial challenges that compromise their wellbeing, yet these realities are poorly captured by...

Gender-responsive and -transformative interventions in HIV, TB and malaria programmes: A review of evidence

2026

Gender-responsive and -transformative interventions are essential for tackling harmful social norms and discriminatory laws, policies, and practices that drive gender inequalities and health inequities especially for women, girls, and gender-diverse...

Prevalence of HIV-associated nephropathy in children: A systematic review with meta-analysis of studies published between 2004 and 2019

2026

Introduction Despite major advances in antiretroviral therapy, HIV infection remains a significant global public health challenge. HIV can directly affect the kidneys, leading to HIV-associated nephropathy in children, a condition...

Factors influencing implementation of point-of-care tests for maternal and newborn screening and diagnosis in low-resource settings: A systematic review

2026

BACKGROUND: Despite the potential of point-of-care (POC) tests to improve maternal and newborn health, implementation in low- and middle-income countries remains inconsistent. POC testing enables rapid, decentralized screening, but barriers...

Comparing clinical outcomes of antibiotics for treating Mycobacterium avium complex infection in adults with HIV: A systematic review and network meta-analysis

2026

Background: This study aims to identify the comparative effects of different drug regimens in treating Mycobacterium avium complex (MAC). Methods: PubMed, EMBASE, CENTRAL, and EBSCO Open Dissertations were searched in September 2023....

Harm reduction progams and interventions for equity-deserving populations who use crack-cocaine. A scoping review

2026

BACKGROUND: Crack-cocaine use is associated with severe physical and mental health consequences, including cardiac, pulmonary and psychiatric conditions. It also heightens the risk of overdose and transmission of infectious diseases...

Efficacy of long-acting injectable cabotegravir and rilpivirine compared with daily oral antiretroviral therapy in patients with HIV: A systematic review

2026

Long-acting antiretroviral therapy (ART) has emerged as an innovative strategy to address limitations associated with daily oral regimens in people living with human immunodeficiency virus type 1 (HIV-1), including adherence...

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