SHARE is an easy-to-search, real-time repository of HIV-related systematic reviews. Whether you’re a researcher, community member, healthcare provider or policymaker, SHARE provides a ‘one-stop shop’ for HIV-related information that has been published through a systematic review.

In addition to systematic reviews published in peer reviewed journals, SHARE also includes Rapid Response reviews produced by the Ontario HIV Treatment Network (OHTN).

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Effectiveness of interventions for changing HIV related risk behaviours among key populations in low-income setting: A meta-analysis, 2001-2016

2020

The aim of this review was to conduct a meta-analysis to assess the effectiveness of behavioural interventions to reduce HIV-related risk behaviours among key populations: people who inject drugs, female...

The safety and efficacy of immune checkpoint inhibitors in patients with advanced cancers and pre-existing chronic viral infections (Hepatitis B/C, HIV): A review of the available evidence

2020

The treatment paradigm of several cancers has dramatically changed in recent years with the introduction of immunotherapy. Most oncology trials involving immune checkpoint inhibitors (ICIPs) have routinely excluded patients with...

A meta-analysis of different types of cardiac adipose tissue in HIV patients

2020

BACKGROUND: Antiretroviral therapy transformed HIV infection into a chronic disease but accelerated cardiovascular disease (CVD). Both of epicardial adipose tissue (EAT) and pericardial fat (PCF) have close relationships with CVD....

Retention in care and viral suppression in differentiated service delivery models for HIV treatment delivery in sub-Saharan Africa: A rapid systematic review

2020

INTRODUCTION: Differentiated service delivery (DSD) models for antiretroviral treatment (ART) for HIV are being scaled up in the expectation that they will better meet the needs of patients, improve the...

mHealth in the prevention of sexually transmitted infections STIs

2020

The objective of this study was to analyze in the literature how the applications were developed and how they influence the prevention of Sexually Transmitted Infections (STIs). PubMed, CAPES Periodicals...

The effects of aerobic training on the CD4 cells, VO2max, and metabolic parameters in HIV-infected patients: A meta-analysis of randomized controlled trials

2020

INTRODUCTION: To our knowledge, there are no systematic review study with meta- analysis that investigated the influence of training variables on specific outcomes (CD4 cell counts) addressed aerobic training for...

Association of antiretroviral therapy with anal high-risk human papillomavirus, anal intraepithelial neoplasia, and anal cancer in people living with HIV: A systematic review and meta-analysis

2020

Background: The effect of antiretroviral therapy (ART) on the natural history of anal high-risk HPV and anal lesion progression is not well established. We reviewed the association of ART and other...

Cognitive and neurologic rehabilitation strategies for central nervous system HIV infection

2020

PURPOSE OF REVIEW: Cognitive impairment leading to disability is increasingly seen in people living with human immunodeficiency virus (PLWH). Rehabilitation can alleviate the effects of cognitive impairment upon function. The...

Acute and early HIV infection screening among men who have sex with men, a systematic review and meta-analysis

2020

INTRODUCTION: Screening for acute and early HIV infections (AEHI) among men who have sex with men (MSM) remains uncommon in sub-Saharan Africa (SSA). Yet, undiagnosed AEHI among MSM and subsequent...

Effect of vitamin D, selenium, or zinc supplementation in HIV: A systematic review

2020

We conducted a systematic review to examine evidence from randomized controlled trials studying the effect of Vitamin D, selenium, or zinc supplementation in human immunodeficiency virus (HIV). An electronic literature...

Factors associated with injecting-related risk behaviors among people who inject drugs: A systematic review and meta-analysis study

2020

We conducted this systematic review and meta-analysis study to better understand the factors (being drug use, drug type (methamphetamine vs others), sex partner, frequency of injection, homelessness and being HIV...

Adolescent mothers affected by HIV and their children: A scoping review of evidence and experiences from sub-Saharan Africa

2020

While adolescents have received increasing attention in the global HIV response and international strategies and commitments, adolescent mothers and their children remain largely overlooked in research, funding and, programming for...

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